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球结膜孢子丝菌病表现为鲑鱼粉色肿瘤。

Bulbar conjunctival sporotrichosis presenting as a salmon-pink tumor.

机构信息

Department of Ophthalmology, Gunma University of Medicine, Maebashi, Gunma, Japan.

出版信息

Cornea. 2010 May;29(5):573-6. doi: 10.1097/ICO.0b013e3181ba7039.

Abstract

PURPOSE

To report a patient with bulbar conjunctival sporotrichosis presenting as a salmon-pink tumor.

METHODS

This was an interventional case report. A 62-year-old woman presented with conjunctival injection in her left eye. Despite administration of topical dexamethasone sodium, ofloxacin, and levocabastine hydrochloride, her symptoms failed to improve and she was referred to us.

RESULTS

Four weeks after referral to us, the patient gradually developed conjunctival injection in both eyes and a salmon-pink tumor in the bulbar conjunctiva of the left eye. Excision biopsy was performed and pathologic examination revealed an epithelioid granuloma with microabscesses and infiltration of plasma cells with yeast-like spherules. A sporotrichin intradermal test was strongly positive. Based on a diagnosis of sporotrichosis, we treated her with topical fluconazole 0.2% in both eyes and oral potassium iodide (450 mg). The bilateral conjunctival injection and subconjunctival tumor in the left eye gradually resolved and had completely disappeared after 3 months of treatment.

CONCLUSION

This is the first report of bulbar conjunctival sporotrichosis with a salmon-pink conjunctival tumor. Although rare, ophthalmologists should be aware of this entity during examination of patients with intractable conjunctival injection.

摘要

目的

报告 1 例表现为鲑粉色肿瘤的球结膜孢子丝菌病。

方法

这是 1 例介入性病例报告。1 名 62 岁女性因左眼结膜充血就诊。尽管给予局部地塞米松钠、氧氟沙星和盐酸左卡巴斯汀治疗,但症状并未改善,并被转至我们医院。

结果

转至我们医院 4 周后,患者逐渐出现双眼结膜充血和左眼球结膜鲑粉色肿瘤。进行了切除活检,病理检查显示存在上皮样肉芽肿,伴有微脓肿和浆细胞浸润,以及酵母样小球体。孢子丝菌素皮内试验呈强阳性。基于孢子丝菌病的诊断,我们给予患者双眼局部氟康唑 0.2%和口服碘化钾(450 mg)治疗。双侧结膜充血和左眼球结膜下肿瘤逐渐消退,治疗 3 个月后完全消失。

结论

这是首例表现为鲑粉色结膜肿瘤的球结膜孢子丝菌病报告。尽管罕见,但眼科医生在检查难治性结膜充血患者时应注意到这种疾病。

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