Suppr超能文献

评估粘连性小肠梗阻患者术后结局的时间趋势和手术亚专科的影响:一项多中心队列研究。

Evaluating temporal trends and the impact of surgical subspecialisation on patient outcomes following adhesional small bowel obstruction: a multicentre cohort study.

机构信息

Department of General Surgery, Forth Valley Royal Hospital, Larbert, Scotland.

Clinical Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, Scotland.

出版信息

Eur J Trauma Emerg Surg. 2023 Jun;49(3):1343-1353. doi: 10.1007/s00068-023-02224-w. Epub 2023 Jan 19.

Abstract

PURPOSE

Small bowel obstruction (SBO) is the most common indication for laparotomy in the UK. While general surgeons have become increasingly subspecialised in their elective practice, emergency admissions commonly remain undifferentiated. This study aimed to assess temporal trends in the management of adhesional SBO and explore the influence of subspecialisation on patient outcomes.

METHODS

Data was collected for patients admitted acutely with adhesional SBO across acute NHS trusts in Northern England between 01/01/02 and 31/12/16, including demographics, co-morbidities and procedures performed. Patients were excluded if a potentially non-adhesional cause was identified and were grouped by the responsible consultant's subspecialty. The primary outcome of interest was 30-day inpatient mortality.

RESULTS

Overall, 2818 patients were admitted with adhesional SBO during a 15-year period. There was a consistent female preponderance, but age and comorbidity increased significantly over time (both p < 0.001). In recent years, more patients were managed operatively with a trend away from delayed surgery also evident (2002-2006: 65.7% vs. 2012-2016: 42.7%, p < 0.001). Delayed surgery was associated with an increased mortality risk on multivariable regression analysis (OR: 2.46 (1.46-4.23, p = 0.001)). CT scanning was not associated with management strategy or timing of surgery (p = 0.369). There was an increased propensity for patients to be managed by gastrointestinal (colorectal and upper gastrointestinal) subspecialists over time. Length of stay (p < 0.001) and 30-day mortality (p < 0.001) both improved in recent years, with the best outcomes seen in colorectal (2.6%) and vascular subspecialists (2.4%). However, following adjustment for confounding variables, consultant subspecialty was not a predictor of mortality.

CONCLUSION

Outcomes for patients presenting with adhesional SBO have improved despite the increasing burden of age and co-morbidity. While gastrointestinal subspecialists are increasingly responsible for their care, mortality is not influenced by consultant subspecialty.

摘要

目的

小肠梗阻(SBO)是英国最常见的剖腹手术指征。虽然普外科医生在他们的择期手术中越来越专业化,但紧急入院的患者通常仍未得到区分。本研究旨在评估粘连性 SBO 管理的时间趋势,并探讨专业化对患者结局的影响。

方法

收集了 2002 年 1 月 1 日至 2016 年 12 月 31 日期间英格兰北部 NHS 信托基金急性入院的粘连性 SBO 患者的数据,包括人口统计学特征、合并症和所进行的手术。如果发现潜在的非粘连性病因,则将患者排除在外,并按负责顾问的专科分组。主要观察指标为 30 天住院死亡率。

结果

总体而言,在 15 年期间有 2818 例患者因粘连性 SBO 入院。尽管女性患者始终占优势,但年龄和合并症在这段时间内显著增加(均 p<0.001)。近年来,越来越多的患者接受手术治疗,手术延迟的趋势也很明显(2002-2006 年:65.7%比 2012-2016 年:42.7%,p<0.001)。多变量回归分析显示,手术延迟与死亡率增加相关(OR:2.46(1.46-4.23,p=0.001))。CT 扫描与管理策略或手术时机无关(p=0.369)。随着时间的推移,患者更倾向于由胃肠(结直肠和上胃肠道)专科医生进行治疗。近年来,住院时间(p<0.001)和 30 天死亡率(p<0.001)均有所改善,结直肠(2.6%)和血管专科医生(2.4%)的效果最佳。然而,在调整混杂变量后,顾问专科并不是死亡率的预测因素。

结论

尽管年龄和合并症的负担增加,但粘连性 SBO 患者的预后有所改善。虽然胃肠科专家越来越负责他们的治疗,但死亡率不受顾问专科的影响。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验