Université de Lorraine, APEMAC, Nancy, France.
Université de Lorraine, CHRU de Nancy, Département Méthodologie Promotion Investigation, F-54000, Nancy, France.
BMC Oral Health. 2023 Jan 18;23(1):29. doi: 10.1186/s12903-023-02727-3.
The use of antibiotics in dental care is often unnecessary or inappropriate. Our objectives were to identify (i) Clusters of dentists grouped according to their appropriateness score based on proxy indicators' results; and (ii) Dentists' and patients' characteristics associated with the appropriateness of antibiotic prescriptions.
We used data of the Health Insurance reimbursement databases on antibiotics prescribed in 2019 by general dental practitioners of the Grand Est region in France. The appropriateness of antibiotic prescriptions was estimated by the results of recently published proxy indicators. We conducted a cluster analysis according to an appropriateness score calculated for each dentist, using the Ward method. We then conducted bivariate and multivariable analyses to identify characteristics associated with these clusters.
We included 3,014 dentists, who prescribed 373,975 antibiotics in 2019, and which were grouped into three clusters: average practices (n = 1,241), better (n = 686), and worse (n = 1,087) than average practices. Overall, dentists had more appropriate prescription practices when they were male (OR for belonging to cluster with "worse than average practices" = 1.37 (p = 0.003) for female), having a predominant surgery practice (p = 0.028) in the Lorraine area (p < 0.0001) for less years (p = 0.0002), when they had healthier patients (i.e., younger, with no chronic diseases, and who received less procedures), and when they had a more prudent use of drugs in general (i.e., less prescriptions of drugs, antibiotics, and non-steroidal anti-inflammatory).
We identified clusters and characteristics associated with the appropriateness of antibiotic prescriptions made by dentists, which might help guiding antimicrobial stewardship interventions.
在牙科护理中使用抗生素通常是不必要的或不适当的。我们的目标是确定:(i)根据代理指标的结果,根据适当性评分对牙医进行分组的聚类;以及(ii)与抗生素处方适当性相关的牙医和患者特征。
我们使用了法国大东部地区 2019 年普通牙科医生开具的抗生素健康保险报销数据库的数据。通过最近发表的代理指标来评估抗生素处方的适当性。我们根据为每位牙医计算的适当性评分,使用 Ward 方法进行聚类分析。然后,我们进行了二变量和多变量分析,以确定与这些聚类相关的特征。
我们纳入了 3014 名牙医,他们在 2019 年共开具了 373975 份抗生素处方,这些处方被分为三个聚类:平均实践(n=1241)、更好(n=686)和更差(n=1087)。总体而言,当牙医为男性(女性属于“低于平均水平”聚类的比值比[OR]为 1.37,p=0.003)、主要从事手术(p=0.028)、在洛林地区(p<0.0001)从业时间较短(p=0.0002)、患者更健康(即年龄较小、无慢性病且接受的治疗较少)、一般药物使用更谨慎(即开具的药物、抗生素和非甾体抗炎药处方较少)时,他们的处方实践更适当。
我们确定了与牙医开具抗生素处方适当性相关的聚类和特征,这可能有助于指导抗菌药物管理干预措施。