V Lakshmi Priya, Johnson Thanka, S Srismitha, Balakrishnan Shobana
Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, IND.
Cureus. 2022 Dec 16;14(12):e32614. doi: 10.7759/cureus.32614. eCollection 2022 Dec.
Cylindroma, a benign skin appendage tumor, mostly occurs in the head and neck region. They present as pink to purple, smooth-surfaced, solitary or multiple nodular lesions, mostly affecting middle-aged and elderly women. A clinical diagnosis of cylindroma is unusual but must be considered clinically. We report an unusual case of solitary benign dermal cylindroma that occurred in an uncommon site in a 54-year-old female. She came with complaints of painful swelling on the left side of her chest wall for six months. Histopathological examination of the mass revealed a well-defined tumor composed of nests and islands of a dual population of tumor cells surrounded by pink basement membrane-like material. These nests of cells are arranged in a "jigsaw" puzzle fashion, which is typical of cutaneous cylindroma. The thick pink material surrounding the epithelial cell islands is periodic acid Schiff stain (PAS) positive.
圆柱瘤是一种良性皮肤附属器肿瘤，多发生于头颈部。表现为粉红色至紫色、表面光滑的孤立或多发结节性病变，多见于中老年女性。圆柱瘤的临床诊断并不常见，但临床上必须予以考虑。我们报告一例罕见的孤立性良性皮肤圆柱瘤病例，发生于一名54岁女性的非常见部位。她因左侧胸壁疼痛性肿胀6个月前来就诊。对该肿物进行组织病理学检查，发现一个边界清晰的肿瘤，由双相肿瘤细胞巢和岛状结构组成，周围有粉红色基底膜样物质。这些细胞巢呈“拼图”样排列，这是皮肤圆柱瘤的典型表现。上皮细胞岛周围的厚粉红色物质对过碘酸希夫染色（PAS）呈阳性。
