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一名克罗恩病患者发生少动鞘氨醇单胞菌所致的自体瓣膜心内膜炎及真菌性脑动脉瘤:病例报告及文献复习

Sphingomonas paucimobilis native valve endocarditis and mycotic cerebral aneurysm in a patient with Crohn's disease: Case report and review of literature.

作者信息

Assi Farah, Hammoud Ramzi, Ezzedine Ahmad, Rahal Hasan

机构信息

Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.

Bahman Hospital, Haret Hreik, Lebanon.

出版信息

IDCases. 2023 Jan 9;31:e01687. doi: 10.1016/j.idcr.2023.e01687. eCollection 2023.

Abstract

This report describes a case of Sphingomonas paucimobilis bacteremia and infective endocarditis with a mycotic aneurysm in a young patient with Crohn's disease. Our patient reported prolonged intermittent fever followed by sudden hemiparesis and a tonic clonic convulsion. His blood cultures showed growth of , and further cardiac imaging revealed the presence of a vegetation with severe valvular regurgitation. Cerebral angiography showed middle cerebral artery occlusion and aneurysm. The patient was treated with meropenem for 6 weeks, coupled with aortic valve replacement, and coiling of the aneurysm. Our patient recovered with good results. is an opportunistic gram-negative pathogen of growing importance in the clinical setting.

摘要

本报告描述了一例少动鞘氨醇单胞菌血症和感染性心内膜炎病例,该病例发生在一名患有克罗恩病的年轻患者身上,伴有霉菌性动脉瘤。我们的患者报告有长期间歇性发热,随后突然出现偏瘫和强直性阵挛性惊厥。他的血培养显示有[具体细菌名称未给出]生长,进一步的心脏影像学检查显示存在赘生物并伴有严重的瓣膜反流。脑血管造影显示大脑中动脉闭塞和动脉瘤。患者接受了美罗培南治疗6周,同时进行了主动脉瓣置换和动脉瘤栓塞术。我们的患者康复情况良好。[具体细菌名称未给出]是一种在临床环境中重要性日益增加的机会性革兰氏阴性病原体。

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