Kengadaran Shivashankar, Anusha Divvi, Baskar Kavya, Muthukrishnan Kavitha, Pooraninagalakshmi J, Prabakar Jayashri
Department of Public Health Dentistry, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth, Pondicherry, India.
Department of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth, Pondicherry, India.
Indian J Dent Res. 2022 Jul-Sep;33(3):332-337. doi: 10.4103/ijdr.ijdr_404_21.
Dental caries is a global oral health problem caused due to localized demineralization of the enamel. Chemical plaque control is used as an adjuvant to mechanical plaque control in removing biofilm, thereby preventing dental caries. In recent times, there has been a renewed interest in nature-based products. This systematic review aimed to analyse the existing literature to compare the effectiveness of herbal and conventional dentifrices on prevention of dental caries. A search was done in the databases of PubMed and Google Scholar in July 2020 for the related topic. A hand search was done from the references of primary studies and other clinical trial registry sites. Randomized control trials, comparative clinical trials, and in vitro studies in which the effectiveness of herbal and conventional dentifrices on prevention of dental caries were included after review by the reviewers. The systematic search revealed a total of thirty-two publications from which ten publications were included. Five studies were clinical studies and five were in vitro studies. All the studies used microbiological analysis for the determination of cariogenic microorganisms in plaque and saliva, whereas one study used pH of plaque and saliva. Among the included studies, all studies had a high risk of bias with level 2 evidence. With the evidence available, it can be concluded that herbal dentifrices and fluoride dentifrices have similar antimicrobial activity against cariogenic microorganisms.
龋齿是一种全球性的口腔健康问题，由牙釉质局部脱矿引起。化学菌斑控制作为机械菌斑控制的辅助手段，用于清除生物膜，从而预防龋齿。近年来，人们对天然产品重新产生了兴趣。本系统评价旨在分析现有文献，比较草药牙膏和传统牙膏在预防龋齿方面的有效性。2020年7月在PubMed和谷歌学术数据库中对相关主题进行了检索。从初步研究的参考文献和其他临床试验注册网站进行了手工检索。随机对照试验、比较临床试验和体外研究，其中草药牙膏和传统牙膏在预防龋齿方面的有效性经评审员审查后纳入。系统检索共发现32篇出版物，其中10篇被纳入。5项研究为临床研究，5项为体外研究。所有研究均采用微生物分析来测定菌斑和唾液中的致龋微生物，而1项研究采用菌斑和唾液的pH值。在所纳入的研究中，所有研究均有较高的偏倚风险，证据等级为2级。根据现有证据，可以得出结论，草药牙膏和含氟牙膏对致龋微生物具有相似的抗菌活性。
