Viallard J F, Roriz M, Parrens M, Bonnotte B
Service de médecine interne et maladies infectieuses, hôpital Haut-Lévêque, CHU de Bordeaux, 5, avenue de Magellan, 33604 Pessac, France.
Service de médecine interne et maladies infectieuses, hôpital d'Agen, Agen, France.
Rev Med Interne. 2022 Dec;43(10S1):10S17-10S25. doi: 10.1016/S0248-8663(23)00021-8.
Clinicians are sometimes confronted with the diagnostic difficulties of the idiopathic form of Castleman's Disease (iMCD). As this review reports with demonstrative clinical cases, iMCD can mimic various serious systemic pathologies such as certain autoimmune diseases, Still's disease, POEMS syndrome, and malignant lymphoproliferations, sharing a very similar histology and identical symptoms. To make a diagnosis of iMCD, the clinician must eliminate all the pathologies mentioned above, but he must first think of it and evoke this diagnosis of rare disease before the first symptoms but also know how to evoke this diagnosis again even after several years of evolution of a disease like those mentioned above whose evolution is not favorable. © 2022 Published by Elsevier Masson SAS on behalf of Société nationale française de médecine interne (SNFMI).
临床医生有时会面临特发性Castleman病（iMCD）的诊断难题。正如本综述通过典型临床病例所报告的那样，iMCD可模仿各种严重的全身性疾病，如某些自身免疫性疾病、斯蒂尔病、POEMS综合征和恶性淋巴增殖性疾病，它们具有非常相似的组织学特征和相同的症状。要诊断iMCD，临床医生必须排除上述所有疾病，但他必须首先想到这种疾病，并在出现最初症状之前就考虑到这种罕见疾病的诊断，而且即使在上述疾病经过数年不利发展之后，也要知道如何再次考虑这种诊断。© 2022由爱思唯尔马松出版社代表法国国家内科医学协会（SNFMI）出版。
