Morris J C, Victor M
Department of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri.
Emerg Med Clin North Am. 1987 Nov;5(4):827-39.
Seizures that occur in relation to alcohol withdrawal, following a period of prolonged intoxication in serious alcoholics, constitute a special syndrome with important prognostic and therapeutic implications. Inpatient management is desirable to eliminate other causes of seizures that occur for the first time in adult life and because such patients are at substantial risk for additional seizures and the development of delirium tremens. Drug therapy with benodiazepines may be effective during the withdrawal period but long-term anticonvulsant treatment is of no value.
在严重酗酒者长期醉酒后发生的与酒精戒断相关的癫痫发作,构成了一种具有重要预后和治疗意义的特殊综合征。对于首次在成年期发生癫痫发作的患者,住院治疗是可取的,因为此类患者有再次发作癫痫和发展为震颤谵妄的重大风险,且住院治疗有助于排除其他病因。在戒断期使用苯二氮䓬类药物进行药物治疗可能有效,但长期抗惊厥治疗并无价值。