Department of Pure and Applied Sciences, University of Urbino "Carlo Bo", Via della Stazione 4, 61029, Urbino, Italy.
Department of Industrial Engineering, University of Florence, via S. Marta 3, 50139, Florence, Italy.
Chempluschem. 2023 May;88(5):e202200364. doi: 10.1002/cplu.202200364. Epub 2023 Jan 19.
The tetranuclear Cu /Ca /Ca2 /Cu complex based on Malten ligand has been investigated as a platform for anion binding. Simple organic carboxylates and non-steroidal anti-inflammatory drugs (NSAIDs) have been tested, revealing the ability of the platform to bind them. The receiving platform hosts at least two guests in solution although a third anion can be bound, as suggested by X-ray diffraction analysis. The addition of the anions is accompanied by a color change of the solution, making the system a colorimetric sensor for carboxylates (LOD values comprised between 3.6 and 20.7 ppm). A fluorescent system consisting of the 2-(3-oxido-6-oxoxanthen-9-yl)benzoate (fluorescein anion) linked to the tetranuclear platform has been also prepared and used in a chemosensing ensemble approach to signal the presence of the selected anions (Log K between 2.6 and 5.6 for the addition of two guests). The latter also works in a paper strip test, offering the chemosensor a possible practical application.
基于 Malten 配体的四核 Cu/ Ca/ Ca2/ Cu 配合物已被研究作为阴离子结合的平台。已经测试了简单的有机羧酸和非甾体抗炎药 (NSAIDs)，揭示了该平台结合它们的能力。尽管 X 射线衍射分析表明可以结合第三个阴离子，但接收平台在溶液中至少可以容纳两个客体。阴离子的加入伴随着溶液颜色的变化，使该系统成为羧酸的比色传感器（LOD 值在 3.6 到 20.7 ppm 之间）。还制备了由 2-(3-氧代-6-氧代氧杂蒽-9-基)苯甲酸酯（荧光素阴离子）与四核平台连接的荧光体系，并用于化学感应组装方法来检测选定阴离子的存在（对于两个客体的添加，Log K 在 2.6 到 5.6 之间）。后者在纸条测试中也有效，为化学传感器提供了一种可能的实际应用。
