Chandran C B, Kitchin A H
Department of Cardiology, Western General Hospital, Edinburgh, U.K.
Eur Heart J. 1987 Aug;8(8):888-94. doi: 10.1093/oxfordjournals.eurheartj.a062353.
We used cross-sectional echocardiography to study left atrial volume changes in 25 patients with mitral valve disease who underwent cardiac catheterisation. Satisfactory 4 chamber views were obtained in 21. Left atrial systolic overload measured as systolic expansion index did not correlate with the severity of mitral regurgitation as assessed by contrast ventriculography and indicator dilution. The left atrial systolic expansion rate, and the maximum volume increase during the first third of systole, measured as the early systolic expansion index, differentiated well between moderate and severe mitral regurgitation, but not between trivial and moderate regurgitation. Calculation of the early systolic expansion fraction (fraction of total expansion occurring in the first third of systole) gave the best correlation with the degree of mitral regurgitation estimated by other methods.
我们采用横断面超声心动图研究了25例接受心导管检查的二尖瓣疾病患者的左心房容积变化。21例获得了满意的四腔心视图。以收缩期扩张指数衡量的左心房收缩期负荷过重与通过对比心室造影和指示剂稀释法评估的二尖瓣反流严重程度无关。左心房收缩期扩张率以及收缩期前三分之一期间的最大容积增加（以早期收缩期扩张指数衡量）在中度和重度二尖瓣反流之间有很好的区分，但在轻度和中度反流之间没有区分。计算早期收缩期扩张分数（收缩期前三分之一发生的总扩张分数）与通过其他方法估计的二尖瓣反流程度具有最佳相关性。
