Kunimoto Mayu, Inomata Minoru, Chin Haruka, Ito Yu, Fujimoto Kazushi, Muto Yutaka, Nomura Moe, Sato Kota, Sakamoto Keita, Awano Nobuyasu, Kuse Naoyuki, Kumasaka Toshio, Takemura Tamiko, Izumo Takehiro
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan.
Department of Hematology, Japanese Red Cross Medical Center, Japan.
Respir Med Case Rep. 2023 Jan 4;42:101807. doi: 10.1016/j.rmcr.2023.101807. eCollection 2023.
Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus type 1-inducing unevenly-distributed T-cell malignancy, which is often complicated by opportunistic infections. Here, we discuss the case of a 75-year-old woman presenting with pneumonia (PCP) who was subsequently diagnosed with ATLL in Tokyo, a non-endemic area of ATLL. In addition to the elevated soluble interleukin-2 receptor and the detection of flower cells in the screening blood test, the high-resolution computed tomography findings, atypical of PCP, were clues to the diagnosis of ATLL. ATLL should be considered as an underlying disease when patients present with PCP, even in non-endemic areas.
成人T细胞白血病/淋巴瘤(ATLL)是一种由1型人类T细胞白血病病毒诱发的T细胞恶性肿瘤,分布不均,常并发机会性感染。在此,我们讨论一名75岁女性的病例,该患者在东京(ATLL非流行地区)出现肺炎(肺孢子菌肺炎),随后被诊断为ATLL。除了筛查血液检查中可溶性白细胞介素-2受体升高和发现花细胞外,高分辨率计算机断层扫描结果(非典型肺孢子菌肺炎)是诊断ATLL的线索。即使在非流行地区,当患者出现肺孢子菌肺炎时,也应考虑ATLL为潜在疾病。