Zafar Saerah Iffat, Halim Aliya, Nasir Hina, Palwa Abdur Rahim, Zafar Nadeem, Burney Shamaila
Department of Radiology, Armed Forces Institute of Radiology and Imaging, Rawalpindi.
Department of Radiology, Islamabad Diagnostic Centre, Rawalpindi.
J Pak Med Assoc. 2022 Oct;72(10):1983-1987. doi: 10.47391/JPMA.3901.
To determine the frequency of ancillary pulmonary signs and their relation to the severity of disease seen on high-resolution computed tomography of chest in patients of coronavirus disease-2019 pneumonia.
The observational descriptive study was conducted at the Armed Forces Institute of Radiology and Imaging, Rawalpindi, Pakistan, from March to July 2020, and included in place of comprised all coronavirus disease-2019 patients who were found positive on reverse transcription-polymerase chain reaction-and were referred to have high-resolution computed tomography of chest. Ancillary pulmonary findings in addition to typical features of coronavirus disease-2019 pneumonia were recorded. These included vacuole sign, halo sign, reverse halo sign, subpleural white line, subpleural translucent line, microvascular dilatation, fibrotic streaks and bronchiectasis. Relative frequency of these signs were determined for mild versus and severe disease, as determined by the computed tomography severity score. Data was analysed using SPSS 26.
Of the 1645 patients, 1286(78.2%) were males and 359(21.8%) were females. The overall mean age was 47.5±15.7 years (range: 1-92). High-resolution computed tomography was normal in 418(25.4%) patients, typical findings for coronavirus disease-2019 were seen in 1110(67.5%), indeterminate in 113(16.9%) and atypical in 4(0.2%). Vacuole sign, subpleural white line, subpleural translucent sign, microvascular dilatation and fibrotic streaks were more commonly seen in severe disease (p<0.001), while discrete pulmonary nodule was identified more in the milder form (p<0.05). Halo and reverse halo signs as well as bronchiectatic changes demonstrated no significant propensity to the degree of disease severity (p>0.05).
Coronavirus disease-2019 pneumonia demonstrated various ancillary pulmonary features on high resolution computed tomography of the chest in addition to typical findings more commonly described; radiologists should be aware of these signs and their relation to disease severity.
确定2019冠状病毒病肺炎患者胸部高分辨率计算机断层扫描中肺部辅助征象的出现频率及其与疾病严重程度的关系。
2020年3月至7月在巴基斯坦拉瓦尔品第武装部队放射学与影像学研究所进行了这项观察性描述性研究，纳入了所有经逆转录聚合酶链反应检测呈阳性且被转诊进行胸部高分辨率计算机断层扫描的2019冠状病毒病患者。记录了2019冠状病毒病肺炎典型特征之外的肺部辅助表现。这些表现包括空泡征、晕征、反晕征、胸膜下白线、胸膜下透光线、微血管扩张、纤维条索和支气管扩张。根据计算机断层扫描严重程度评分确定这些征象在轻症和重症疾病中的相对出现频率。使用SPSS 26对数据进行分析。
1645例患者中，男性1286例（78.2%），女性359例（21.8%）。总体平均年龄为47.5±15.7岁（范围：1 - 92岁）。418例（25.4%）患者的高分辨率计算机断层扫描结果正常，1110例（67.5%）出现2019冠状病毒病的典型表现，113例（16.9%）表现不明确，4例（0.2%）表现不典型。空泡征、胸膜下白线、胸膜下透光征、微血管扩张和纤维条索在重症疾病中更常见（p<0.001），而孤立性肺结节在轻症中更常见（p<0.05）。晕征和反晕征以及支气管扩张改变在疾病严重程度方面无明显倾向（p>0.05）。
2019冠状病毒病肺炎在胸部高分辨率计算机断层扫描中除了更常见的典型表现外，还表现出各种肺部辅助特征；放射科医生应了解这些征象及其与疾病严重程度的关系。
