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[氨苯酸作用对记忆痕迹提取的促进作用]

[Facilitation of memory trace retrieval by the action of amfonelic acid].

作者信息

Il'iuchenok R Iu, Dubrovina N I, Vinnitskiĭ I M

出版信息

Farmakol Toksikol. 1987 Jul-Aug;50(4):22-5.

PMID:3666112
Abstract

Amfonelic acid exerting the central dopaminergic effect was studied on mice by the passive avoidance conditioned response method under amnesia induced by leaving the animals in a dark chamber following electrocutaneous stimulation and different terms of natural forgetting. Amfonelic acid was shown to prevent the amnesic effect, to improve retrieval of the conditioned response decreased as a result of amnesia or prolonged forgetting.

摘要

采用被动回避条件反应法,在电皮肤刺激后将动物置于暗室诱导的遗忘以及不同时长自然遗忘所导致的失忆状态下,对小鼠进行了发挥中枢多巴胺能效应的安福尼酸的研究。结果表明,安福尼酸可预防失忆效应,改善因失忆或长期遗忘而降低的条件反应恢复能力。

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