Amenta D, Cavallotti C, De Rossi M, Ferrante F, Amenta F
Department of Neurological Sciences, La Sapienza University, Rome, Italy.
Funct Neurol. 1987 Apr-Jun;2(2):207-16.
By the use of combined radioreceptor binding and autoradiographic techniques, we analyzed the anatomical localization of the dopaminergic agonist 3H-dihydroergotoxine in tissue sections of rat male sex organs. The drug was bound by smooth muscle cells of the deferent duct, seminal vesicles and prostate gland as well as by the glandular tissue of seminal vesicles and prostate gland. These data allow us to hypothesize that the effect of dopaminergic agonists on male sexual function may be due, at least in part, to a direct interaction with dopamine receptors present in the reproductive organs.
通过联合使用放射受体结合和放射自显影技术，我们分析了多巴胺能激动剂3H-二氢麦角隐亭在大鼠雄性性器官组织切片中的解剖定位。该药物与输精管、精囊和前列腺的平滑肌细胞以及精囊和前列腺的腺组织结合。这些数据使我们能够推测，多巴胺能激动剂对男性性功能的影响可能至少部分归因于与生殖器官中存在的多巴胺受体的直接相互作用。
