基于聚羟基丁酸酯（PHB）并经氯高铁血红素改性的电纺纤维材料的生物相容性和抗菌活性

Biocompatibility and Antimicrobial Activity of Electrospun Fibrous Materials Based on PHB and Modified with Hemin.

作者信息

Tyubaeva Polina M, Varyan Ivetta A, Nikolskaya Elena D, Mollaeva Mariia R, Yabbarov Nikita G, Sokol Maria B, Chirkina Margarita V, Popov Anatoly A

机构信息

Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia.

Academic Department of Innovational Materials and Technologies Chemistry, Plekhanov Russian University of Economics, 36 Stremyanny Per., 117997 Moscow, Russia.

出版信息

Nanomaterials (Basel). 2023 Jan 5;13(2):236. doi: 10.3390/nano13020236.

The effect of the hemin (Hmi) on the structure and properties of nanocomposite electrospun materials based on poly-3-hydroxybutyrate (PHB) is discussed in the article. The additive significantly affected the morphology of fibers allowed to produce more elastic material and provided high antimicrobial activity. The article considers also the impact of the hemin on the biocompatibility of the nonwoven material based on PHB and the prospects for wound healing.