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沉淀型疏水性可注射液体(PHIL)在大型耳后动静脉畸形术前血管栓塞中的新应用。

Novel use of precipitating hydrophobic injectable liquid (PHIL) in pre-operative angioembolisation of a large posterior auricular arteriovenous malformation.

作者信息

Chu Clarisse, Tan Toh Hui Leonard, Ng Keng Sin, Tan Chien Sheng, Lee Tee Sin, Yuen Heng Wai, Lee Wickly, Huang Xin Yong

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Changi General Hospital, Singapore, Singapore.

Department of Otorhinolaryngology, Head and Neck Surgery, Changi General Hospital, Singapore, Singapore.

出版信息

Am J Otolaryngol. 2023 Mar-Apr;44(2):103786. doi: 10.1016/j.amjoto.2022.103786. Epub 2023 Jan 6.

DOI:10.1016/j.amjoto.2022.103786
PMID:36680841
Abstract

BACKGROUND

Large arteriovenous malformations are often managed via endovascular embolisation followed by surgical resection. We describe the use of a new liquid embolic agent (LEA) - precipitating hydrophobic injectable liquid (PHIL) and its advantages over existing LEAs.

CASE

A 60-year-old male presented with a progressively enlarging right post-auricular arteriovenous malformation. He underwent successive angioembolisation with PHIL and subsequent surgical resection on post-embolisation day 1.

CONCLUSION

To our knowledge, this is the first reported case of PHIL being used in pre-operative embolization of a large extra-cranial head and neck AVM. Its excellent penetration into small calibre vessels, decreased glare artefact on imaging and decreased skin pigmentation render it a compelling alternative to existing LEAs.

摘要

背景

大型动静脉畸形通常先通过血管内栓塞治疗,然后进行手术切除。我们描述了一种新型液体栓塞剂(LEA)——沉淀型疏水性可注射液体(PHIL)的使用及其相对于现有液体栓塞剂的优势。

病例

一名60岁男性,右耳后动静脉畸形逐渐增大。他在栓塞术后第1天接受了PHIL连续血管内栓塞及后续手术切除。

结论

据我们所知,这是首例报道将PHIL用于大型颅外头颈部动静脉畸形术前栓塞的病例。它能很好地穿透小口径血管,减少成像时的眩光伪影,并减少皮肤色素沉着,使其成为现有液体栓塞剂的有力替代物。

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