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比较三种不同技术的胸部断层扫描对健康患者癌症风险的影响。

Cancer risk in healthy patients who underwent chest tomography comparing three different technologies.

作者信息

Pedrosa K F S, Engler C, Nogueira M S

机构信息

Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN, Av. Pres. Antônio Carlos, 6627, 31270-901, Belo Horizonte, MG, Brazil.

Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN, Av. Pres. Antônio Carlos, 6627, 31270-901, Belo Horizonte, MG, Brazil.

出版信息

Appl Radiat Isot. 2023 Mar;193:110625. doi: 10.1016/j.apradiso.2022.110625. Epub 2022 Dec 29.

DOI:10.1016/j.apradiso.2022.110625
PMID:36680979
Abstract

This research aimed to estimate the risk of cancer associated with patients without previous disease undergoing chest tomography. Siemens CT scanners have 6, 64, and 128 detectors. The Biologic Effects of Ionizing Radiation Reports - BEIR VII methodology was used. The study presented a sample of 64 patients aged between 18 and 80 years, in the city of Belo Horizonte, Minas Gerais - Brazil. The IMPACT CT software and CalDose X CT Online were used to calculate the absorbed and equivalent dose from the Volumetric Computed Tomography Dose Index - CTDIvol (mGy) and Dose Length Product - DLP values provided by the equipment. CT-Expo Software was also used to estimate Specific Dose Estimates (SSDEs) values. The CTDvol results for the MG1, MG,2 and MG3 Diagnostic Centers in mGy were respectively 4.369 ± 1.352, 6.99 4 ± 1.53,3 and 9.984 ± 2.282 and the SSDE values were 3.800, 6.40,0 and 9,.500. The values for the equivalent dose, at the MG2 Diagnostic Center, by IMPACT CT, in (mSv) for the breasts, esophagus, heart, thyroid, lung and thymus were respectively 3.9, 5.7, 4.7, 1.0, 4.8 and 5.7. The CalDose Software, for the same equipment and the same organs, in mSv, estimated the values 7.4, 9.4, 11.1, 5.3, 10.8 and 11.3 for women and 7.1, 9.3, 11.0, 5.3, 10.2 and 10.9 for men. The estimated risk of cancer decreased according to the patient's age, but with a higher incidence for females. The use of each software must be carefully analyzed to avoid undue values due to the particularities of each one. The results also showed that the risk of developing cancer due to radiation decreases with patient age and is higher in females.

摘要

本研究旨在评估先前无疾病的患者进行胸部断层扫描时患癌症的风险。西门子CT扫描仪有6排、64排和128排探测器。采用了《电离辐射生物效应报告 - BEIR VII》的方法。该研究选取了巴西米纳斯吉拉斯州贝洛奥里藏特市64名年龄在18至80岁之间的患者作为样本。使用IMPACT CT软件和CalDose X CT Online根据设备提供的容积计算机断层扫描剂量指数 - CTDIvol(mGy)和剂量长度乘积 - DLP值来计算吸收剂量和当量剂量。还使用CT - Expo软件来估算特定剂量估计值(SSDEs)。MG1、MG2和MG3诊断中心的CTDvol结果(单位为mGy)分别为4.369±1.352、6.994±1.533和9.984±2.282,SSDE值分别为3.800、6.400和9.500。在MG2诊断中心,通过IMPACT CT计算的乳房、食管、心脏、甲状腺、肺和胸腺的当量剂量(单位为mSv)分别为3.9、5.7、4.7、1.0、4.8和5.7。对于相同设备和相同器官,CalDose软件估算的女性当量剂量值(单位为mSv)为7.4、9.4、11.1、5.3、10.8和11.3,男性为7.1、9.3、11.0、5.3、10.2和10.9。患癌症的估计风险随患者年龄降低,但女性发病率更高。必须仔细分析每个软件的使用情况,以避免因各自的特殊性而出现不当值。结果还表明,因辐射患癌症的风险随患者年龄降低,且女性风险更高。

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