Hargittay Csenge, Vörös Krisztián, Eőry Ajándék, Márkus Bernadett, Szabó Georgina, Rihmer Zoltán, Gonda Xénia, Torzsa Péter
1 Semmelweis Egyetem, Általános Orvostudományi Kar, Családorvosi Tanszék 1428 Budapest, Pf. 2 Magyarország.
2 Semmelweis Egyetem, Általános Orvostudományi Kar, Mentális Egészségtudományok Doktori Iskola Budapest Magyarország.
Orv Hetil. 2023 Jan 22;164(3):79-87. doi: 10.1556/650.2023.32676.
The bidirectional relationship between diabetes and depression results in severe disease burden. Co-occurring depression is associated with a higher rate of diabetes complications. These complications impair quality of life, however, their impact on depressive symptoms is controversial.
In our cross-sectional study, we aimed to investigate whether the presence of diabetes complications is associated with depressive and anxiety symptoms among patients with type 2 diabetes in general practice.
We obtained patient history, anthropometric, socioeconomic, laboratory parameters. For symptom assessment, the Beck Depression Inventory (BDI) and the Hamilton Anxiety Scale (HAM-A) were used. We collected data between September 2018 and February 2020.
We included 338 consecutive patients with type 2 diabetes. The mean age of the sample was 63.98 ± 11.51 (years ± SD), 61.2% of participants were female. We found significant univariate association between diabetes complications and older age, less physical activity, higher body mass index, insulin therapy, higher HbA1c, higher creatinine and carbamide concentrations, worse depressive and anxiety symptoms. In multivariate analysis, diabetes complications and certain socio-demographic factors (female gender, lower education, rural-dwelling) were the determinants of higher BDI and HAM-A scores.
Among primary care patients with type 2 diabetes, the prevalence of depressive and anxiety symptoms was higher and more severe in patients with diabetes complications. The recommended screening for affective disorders among patients with diabetes is especially justified if complications are present. Orv Hetil. 2023; 164(3): 79-87.
糖尿病与抑郁症之间的双向关系导致了严重的疾病负担。同时存在的抑郁症与糖尿病并发症的发生率较高有关。这些并发症会损害生活质量，然而，它们对抑郁症状的影响存在争议。
在我们的横断面研究中，我们旨在调查在全科医疗中，2型糖尿病患者糖尿病并发症的存在是否与抑郁和焦虑症状相关。
我们获取了患者病史、人体测量数据、社会经济状况、实验室参数。对于症状评估，使用了贝克抑郁量表（BDI）和汉密尔顿焦虑量表（HAM - A）。我们在2018年9月至2020年2月期间收集数据。
我们纳入了338例连续的2型糖尿病患者。样本的平均年龄为63.98±11.51（岁±标准差），61.2%的参与者为女性。我们发现糖尿病并发症与年龄较大、身体活动较少、体重指数较高、胰岛素治疗、糖化血红蛋白（HbA1c）较高、肌酐和尿素浓度较高、抑郁和焦虑症状较差之间存在显著的单变量关联。在多变量分析中，糖尿病并发症和某些社会人口学因素（女性、教育程度较低、居住在农村）是BDI和HAM - A得分较高的决定因素。
在初级保健的2型糖尿病患者中，有糖尿病并发症的患者抑郁和焦虑症状的患病率更高且更严重。如果存在并发症，建议对糖尿病患者进行情感障碍筛查尤其合理。《匈牙利医学周报》。2023年；164(3):79 - 87。
