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社会不平等与精神病性体验沿着广义精神病表型的发生、持续及进展之间的关联:一项基于社区样本的6年随访研究

The association of social inequality with the onset, persistence, and progression of psychotic experiences along the extended psychosis phenotype: a 6-year follow-up study in a community-based sample.

作者信息

Binbay Tolga, Erel Batuhan, Set Rana Tibet, Kırlı Umut, Ergül Ceylan, Elbi Hayriye, Alptekin Köksal

机构信息

Department of Psychiatry, Faculty of Medicine, Dokuz Eylül University, 35340, Izmir, Turkey.

Çınarcık State Hospital, Yalova, Turkey.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2024 Jan;59(1):51-64. doi: 10.1007/s00127-023-02422-2. Epub 2023 Jan 22.

Abstract

PURPOSE

This paper aims to investigate associations between early childhood and current indicators of socioeconomic inequality and the onset (incident), persistence and progression (increase in severity) of psychotic experiences (PEs) in a longitudinal follow-up of a community-based population.

METHODS

Households in the metropolitan area of Izmir, Turkey were contacted in a multistage clustered probability sampling frame, at baseline (T, n = 4011) and at 6-year follow-up (T, n = 2185). Both at baseline and follow-up, PEs were assessed using Composite International Diagnostic Interview 2.1. The associations between baseline socioeconomic features and follow-up PEs were analysed using logistic regression models. Indicators of social inequality included income, educational level, current socioeconomic status (SES), social insurance, the area resided, ethnicity, parental educational level, and SES at birth.

RESULTS

The risk of onset of PEs was significantly higher in lower education, lower SES, and slum-semi-urban areas. The persistence of PEs was significantly associated with the lowest levels of education and current SES, and rural residency. Persistent PEs were significantly and negatively associated with paternal SES at birth. Progression of PEs was significantly higher among respondents with educational achievements lower than university level and lower levels of SES, who have no social insurance and who reside in slum-semi-urban areas. Parental education and paternal SES at birth were not associated with the persistence of PEs.

CONCLUSION

Indicators of social inequality (low education, low SES, low income, and poverty in the neighbourhood) were associated with the onset and persistence of PEs and progression along the extended psychosis phenotype. The early indicators seem to have a modest life-long impact on the psychosis phenotype.

摘要

目的

本文旨在通过对社区人群的纵向随访,研究儿童早期社会经济不平等指标与当前指标以及精神病性体验(PEs)的发病(新发)、持续存在和进展(严重程度增加)之间的关联。

方法

在土耳其伊兹密尔都会区,采用多阶段整群概率抽样框架,在基线期(T1,n = 4011)和6年随访期(T2,n = 2185)对家庭进行联系。在基线期和随访期,均使用复合国际诊断访谈2.1评估PEs。使用逻辑回归模型分析基线社会经济特征与随访期PEs之间的关联。社会不平等指标包括收入、教育水平、当前社会经济地位(SES)、社会保险、居住地区、种族、父母教育水平以及出生时的SES。

结果

在低教育水平、低SES以及贫民窟 - 半城市地区,PEs发病风险显著更高。PEs的持续存在与最低教育水平、当前SES以及农村居住显著相关。持续性PEs与出生时父亲的SES显著负相关。在教育成就低于大学水平、SES较低、没有社会保险且居住在贫民窟 - 半城市地区的受访者中,PEs的进展显著更高。父母教育水平和出生时父亲的SES与PEs的持续存在无关。

结论

社会不平等指标(低教育水平、低SES、低收入以及邻里贫困)与PEs的发病、持续存在以及沿着扩展精神病表型的进展相关。早期指标似乎对精神病表型有适度的终生影响。

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