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成年移民和少数族裔中的亚临床精神病:系统评价与荟萃分析。

Subclinical psychosis in adult migrants and ethnic minorities: systematic review and meta-analysis.

作者信息

Tortelli Andrea, Nakamura Aurélie, Suprani Federico, Schürhoff Franck, Van der Waerden Judith, Szöke Andrei, Tarricone Ilaria, Pignon Baptiste

机构信息

U955-15, INSERM, Créteil and Pôle GHT Psychiatrie Précarité, Paris, France.

UMR_S 1136, INSERM, Pierre Louis Institute of Epidemiology and Public Health, Sorbonne Universités, France.

出版信息

BJPsych Open. 2018 Nov 23;4(6):510-518. doi: 10.1192/bjo.2018.68. eCollection 2018 Nov.

Abstract

BACKGROUND

It is well established that migration and ethnic minority status are risk factors for psychotic disorders. Recent studies have aimed to determine if they are also associated with subclinical psychosis (psychotic-like experiences and schizotypal traits).

AIMS

We aimed to determine to what extent migrant and ethnic minority groups are associated with higher risk of subclinical psychosis.

METHOD

We conducted a systematic review, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and examined findings by ethnicity, migrant status, outcomes of subclinical psychosis and host country. A meta-analysis was carried out with robust variance estimation where possible, to handle statistically dependent effect size estimates.

RESULTS

We included 28 studies (19 studies on psychotic-like experiences and 9 studies on schizotypal traits) and found that ethnicity, but not migrant status, was associated with current and lifetime psychotic-like experiences. In the narrative analysis, we observed the effect of psychosocial risk factors on this association: Black ethnicity groups showed consistent increased prevalence of current and lifetime psychotic-like experiences compared with the reference population across countries.

CONCLUSIONS

More generalisable and standardised cohort studies of psychotic-like experiences and schizotypal traits in relation to migration/ethnicity are necessary to examine the effects of exposures and outcomes in different contexts, and to understand the underlying mechanisms of the association between subclinical psychosis and migrant and ethnic minority status.

DECLARATION OF INTEREST

None.

摘要

背景

迁移和少数族裔身份是精神障碍的危险因素,这一点已得到充分证实。近期研究旨在确定它们是否也与亚临床精神病(类精神病体验和分裂型特质)有关。

目的

我们旨在确定移民群体和少数族裔群体在多大程度上与亚临床精神病的较高风险相关。

方法

我们使用系统评价与Meta分析的首选报告项目声明进行了一项系统评价,并按种族、移民身份、亚临床精神病结局和东道国对研究结果进行了审查。在可能的情况下,进行了稳健方差估计的Meta分析,以处理统计上相关的效应量估计值。

结果

我们纳入了28项研究(19项关于类精神病体验的研究和9项关于分裂型特质的研究),发现种族而非移民身份与当前和终生类精神病体验有关。在叙述性分析中,我们观察到社会心理风险因素对这种关联的影响:与各国的参照人群相比,黑人种族群体当前和终生类精神病体验的患病率持续增加。

结论

有必要开展关于类精神病体验和分裂型特质与迁移/种族关系的更具普遍性和标准化的队列研究,以考察不同背景下暴露因素和结局的影响,并了解亚临床精神病与移民和少数族裔身份之间关联的潜在机制。

利益声明

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b710/6293451/6b09f183827f/S2056472418000686_fig1.jpg

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