Jiang Haote, Sun Mengxiao, Shao Rongrong, Su Shuyue, Zhang Yuyang
The First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.
Department of Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Front Surg. 2023 Jan 5;9:939034. doi: 10.3389/fsurg.2022.939034. eCollection 2022.
This study was performed to assess the association of calcium channel blockers (CCB) and other potential factors with postoperative lymphatic-related morbidity in patients with cervical cancer and endometrial carcinoma.
Patients diagnosed with cervical cancer or endometrial carcinoma with pelvic lymphadenectomy between January 2017 and January 2022 were enrolled. Postoperative lymphatic-related morbidity was evaluated by calculating the lymph cyst occurrence within 3 months after surgery and the duration of pelvic drainage. Univariate analyses evaluating the risk factors for lymphatic-related morbidity were performed.
Of a total of 251 patients, 52 patients were diagnosed with lymphatic cysts by B-ultrasound or computed tomography, and the duration of drainage from 110 patients exceeded the average number of days. Univariable analysis revealed that hypertension, CCB, and lymph node metastasis were independent predictors of postoperative complications.
This study demonstrated that CCB may be a factor associated with the incidence of postoperation lymph cysts, and CCB usage prolongs the duration of pelvic drainage.
本研究旨在评估钙通道阻滞剂（CCB）及其他潜在因素与宫颈癌和子宫内膜癌患者术后淋巴相关并发症的关联。
纳入2017年1月至2022年1月期间诊断为宫颈癌或子宫内膜癌并接受盆腔淋巴结清扫术的患者。通过计算术后3个月内淋巴囊肿的发生率和盆腔引流持续时间来评估术后淋巴相关并发症。对淋巴相关并发症的危险因素进行单因素分析。
在总共251例患者中，52例经B超或计算机断层扫描诊断为淋巴囊肿，110例患者的引流持续时间超过平均天数。单因素分析显示，高血压、CCB和淋巴结转移是术后并发症的独立预测因素。
本研究表明CCB可能是与术后淋巴囊肿发生率相关的一个因素，且使用CCB会延长盆腔引流时间。
