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蛛网膜下腔出血后总循环血容量的测量:方法学方面。

Measurement of total circulating blood volume following subarachnoid haemorrhage: methodological aspects.

作者信息

Nelson R J, Roberts J, Ackery D M, Pickard J D

机构信息

Wessex Neurological Centre, Southampton General Hospital, UK.

出版信息

J Neurol Neurosurg Psychiatry. 1987 Sep;50(9):1130-5. doi: 10.1136/jnnp.50.9.1130.

Abstract

The total circulating blood volume (TCBV) and total body/venous haematocrit ratio (Htb/Hv) was determined by simultaneous measurement of the red cell volume (RCV) and the plasma volume (PV) in 10 subarachnoid haemorrhage (SAH) patients, 10 supine bedresting control patients and 20 ambulant out-patients. The mean Htb/Hv of the SAH patients, 0.866, was found to be significantly lower than that of the supine controls, 0.908, and the ambulant patients, 0.909, (p less than 0.01). Using the ratio 0.866 the total circulating blood volume of the SAH patients was calculated from either their RCV or their PV and compared with their measured TCBV. Expressed as a percentage of measured TCBV the mean errors of these single volume determinations were 2.84% and 1.76% respectively. The significance of these changes in the Htb/Hv ratio of SAH patients is discussed in relation to the circulatory disturbances they suffer.

摘要

通过同时测量10例蛛网膜下腔出血(SAH)患者、10例仰卧位卧床对照患者和20例门诊活动患者的红细胞容积(RCV)和血浆容积(PV),测定了总循环血量(TCBV)和全身/静脉血细胞比容比值(Htb/Hv)。发现SAH患者的平均Htb/Hv为0.866,显著低于仰卧位对照患者的0.908和门诊活动患者的0.909(p<0.01)。使用0.866这个比值,根据SAH患者的RCV或PV计算出他们的总循环血量,并与测量得到的TCBV进行比较。以测量得到的TCBV的百分比表示,这些单一容积测定的平均误差分别为2.84%和1.76%。结合SAH患者所遭受的循环紊乱,讨论了其Htb/Hv比值这些变化的意义。

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