Honan W P, Heron J R, Foster D H, Snelgar R S
Department of Neurology, North Staffordshire Royal Infirmary, Stoke-on-Trent, UK.
J Neurol Neurosurg Psychiatry. 1987 Sep;50(9):1160-4. doi: 10.1136/jnnp.50.9.1160.
Six cases of multiple sclerosis are reported in which cold produced a temporary exacerbation of symptoms and signs of the disease. Also, in one case investigated in detail by psychophysical methods, heating produced a paradoxical deterioration in vision and simultaneous improvement in sensory and motor function. The effect of temperature in multiple sclerosis is discussed and a physiological explanation for the paradoxical response to heating is suggested.
报告了6例多发性硬化症患者,其中寒冷导致该疾病的症状和体征暂时加重。此外,在通过心理物理学方法详细研究的1例患者中,加热导致视力反常恶化,同时感觉和运动功能改善。讨论了温度对多发性硬化症的影响,并提出了对加热产生反常反应的生理学解释。