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1例通过镓- DOTATOC正电子发射断层扫描/计算机断层扫描偶然发现颈髓血管母细胞瘤的罕见病例。

A Rare Case of Incidental Finding of Cervical Spinal Cord Hemangioblastoma by Ga-DOTATOC Positron Emission Tomography/Computed Tomography Scan.

作者信息

Bellini Pietro, Dondi Francesco, Albano Domenico, Bertagna Francesco

机构信息

Departement of Nuclear Medicine, Spedali Civili di Brescia and Università Degli Studi di Brescia, Brescia, Italy.

出版信息

Indian J Nucl Med. 2022 Jul-Sep;37(3):259-260. doi: 10.4103/ijnm.ijnm_197_21. Epub 2022 Nov 2.

DOI:10.4103/ijnm.ijnm_197_21
PMID:36686292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9855231/
Abstract

Hemangioblastomas are rare vascular tumors of the central nervous system usually related to other pathological conditions, such as Von Hippel Lindau Syndrome (VHLS) and polycythemia. We describe a case of a 65-year-old man with a neuroendocrine tumor of the ileum presenting with cervical pain who underwent a Ga-DOTATOC positron emission tomography/computed tomography (PET/CT) scan that incidentally underlines the presence of hemangioblastoma of the cervical spinal cord. The patient does not have a family history of VHLS nor does he suffer from polycythemia and he is currently waiting for genetic testing. Despite being rare, hemangioblastomas could be possible findings of central nervous system incidentaloma at Ga-DOTATOC PET/CT scan, especially in patients with anamnesis with possible related condition.

摘要

血管母细胞瘤是中枢神经系统罕见的血管性肿瘤,通常与其他病理状况相关,如冯·希佩尔-林道综合征(VHLS)和红细胞增多症。我们描述了一例65岁男性,患有回肠神经内分泌肿瘤,表现为颈部疼痛,接受了镓- DOTATOC正电子发射断层扫描/计算机断层扫描(PET/CT),该检查意外发现了颈髓血管母细胞瘤。该患者没有VHLS家族史,也未患红细胞增多症,目前正在等待基因检测。尽管血管母细胞瘤罕见,但在镓- DOTATOC PET/CT扫描中可能是中枢神经系统偶发瘤的发现,尤其是在有相关可能病史的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d7/9855231/66e646a89483/IJNM-37-259-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d7/9855231/6bee691f30d6/IJNM-37-259-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d7/9855231/66e646a89483/IJNM-37-259-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d7/9855231/6bee691f30d6/IJNM-37-259-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16d7/9855231/66e646a89483/IJNM-37-259-g002.jpg

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本文引用的文献

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Incidental uterine fibroid detected by Ga-DOTATOC PET/CT scan in patient with ileal neuroendocrine tumor.在一名回肠神经内分泌肿瘤患者中,通过镓- DOTATOC PET/CT扫描偶然发现子宫纤维瘤。
Rev Esp Med Nucl Imagen Mol (Engl Ed). 2021 Sep-Oct;40(5):334-336. doi: 10.1016/j.remnie.2020.07.002. Epub 2020 Aug 23.
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Pearls and Pitfalls in Interpretation of 68Ga-DOTATOC PET Imaging.68Ga-DOTATOC PET 成像解读的要点与陷阱。
Clin Nucl Med. 2020 Jun;45(6):e279-e280. doi: 10.1097/RLU.0000000000003012.
3
Cerebellar haemangioblastoma discovered incidentally on (68)Ga-DOTA-octreotate examination.
在(68)镓-多胺基多羧基环肽奥曲肽检查中偶然发现的小脑血管母细胞瘤。
Clin Neurol Neurosurg. 2016 May;144:20-2. doi: 10.1016/j.clineuro.2016.02.028. Epub 2016 Feb 26.
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Von Hippel-Lindau disease.冯·希佩尔-林道病
Handb Clin Neurol. 2015;132:139-56. doi: 10.1016/B978-0-444-62702-5.00010-X.
5
Von Hippel-Lindau syndrome: demonstration of entire disease spectrum with (68)Ga-DOTANOC PET-CT.希佩尔-林道综合征:(68)Ga-DOTANOC PET-CT 显示全疾病谱。
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