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病灶内注射甲基强的松龙治疗眼眶和颅骨朗格汉斯细胞组织细胞增多症。

Intralesional methylprednisolone for Langerhans' cell histiocytosis of the orbit and cranium.

作者信息

Wirtschafter J D, Nesbit M, Anderson P, McClain K

机构信息

Department of Ophthalmology, University of Minnesota Hospital, Minneapolis 55455.

出版信息

J Pediatr Ophthalmol Strabismus. 1987 Jul-Aug;24(4):194-7. doi: 10.3928/0191-3913-19870701-11.

Abstract

A 27-month-old girl had a rapidly expanding orbital frontal bone mass due to Langerhans' cell histiocytosis. The CT of the orbit showed a lateral orbital mass containing an irregular density that extended into the intracranial cavity through a lytic lesion of the bone. This is the first report of the use in the orbit of an intralesional steroid injection. Five months later the lesion had not recurred. This treatment spared the patient radiation therapy or a craniotomy with curettage.

摘要

一名27个月大的女孩因朗格汉斯细胞组织细胞增多症出现眼眶额骨肿块迅速增大。眼眶CT显示外侧眼眶肿块,密度不规则,通过骨质溶解病变延伸至颅内腔。这是关于病灶内注射类固醇用于眼眶治疗的首例报告。五个月后,病灶未复发。这种治疗方法使患者免于放射治疗或开颅刮除术。

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