Yang Jae Won
Division of Nephrology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
The Korean Society of Geriatric Nephrology, Seoul, Republic of Korea.
Electrolyte Blood Press. 2022 Dec;20(2):57-63. doi: 10.5049/EBP.2022.20.2.57. Epub 2022 Dec 30.
In elderly chronic kidney disease (CKD) patients, isolated systolic hypertension is common, the rate of renal function decline is slow, and there is a high possibility of physical damage due to side effects such as drug use-related orthostatic hypotension. Therefore, there are still many questions about whether lowering blood pressure in elderly patients will actually improve prognosis. Since many blood pressure-related clinical studies exclude advanced CKD and the elderly, it is particularly difficult to define target blood pressure in these populations. A randomized controlled trial is needed to establish optimal blood pressure targets and treatment strategies in elderly patients with CKD. This review seeks to summarize the guidelines available at this time.
在老年慢性肾脏病(CKD)患者中,单纯收缩期高血压很常见,肾功能下降速度缓慢,且因药物使用相关的体位性低血压等副作用导致身体损伤的可能性很高。因此,关于老年患者降低血压是否真的能改善预后仍存在许多问题。由于许多与血压相关的临床研究排除了晚期CKD患者和老年人,在这些人群中确定目标血压尤为困难。需要进行一项随机对照试验,以确立老年CKD患者的最佳血压目标和治疗策略。本综述旨在总结目前可用的指南。