Division of Environmental Health Sciences, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA
Masonic Cancer Center, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Tob Control. 2024 Jun 20;33(4):541-544. doi: 10.1136/tc-2022-057571.
Regulation of filter ventilation (FV) has been proposed to reduce misperceptions that ventilation reduces the health risks of smoking. We describe smoking behaviour and exposure after switching to a cigarette brand variant (CBV) with a different FV level.
Wave 1 (2013-2014) of the Population Assessment of Tobacco Use and Health Study was merged with FV levels of participants' CBV and restricted to adults with a usual CBV, smoked daily and included in wave 4 (2016-2017; n=371). Generalised estimation equations method modelled changes in FV and cigarettes per day (CPD), quit interest, total nicotine equivalents (TNE) and total NNAL (biomarker of a tobacco-specific carcinogen). FV change was defined as a change in CBV resulting in a ≥20% increase or decrease in FV. Secondary analyses used FV change based on an from <5% to >10% or a from >10% to <5%.
A non-significant pattern indicating an increase of 0.97 and 0.49 CPD was observed among those who switched to a CBV and increased FV by ≥20% and from <5% to >10%, respectively. A non-significant pattern indicating a decrease of 1.31 and 1.97 CPD was observed among those who decreased FV by ≥20% and from >10% to <5%, respectively. Changes in quit interest and biomarkers were also non-significant with one exception: greater reduction in TNE among those who decreased from >10% to <5% FV versus no change (-8.51 vs -0.25 nmol/mg creatinine; p=0.0447).
Switching to CBV with lower FV does not appear to increase exposure and may even reduce exposure for some. Additional investigations are recommended to confirm these descriptive findings.
调节过滤通风(FV)已被提议用于减少对通风降低吸烟健康风险的误解。我们描述了在切换到具有不同 FV 水平的香烟品牌变体(CBV)后的吸烟行为和暴露情况。
将 2013-2014 年人群烟草使用和健康评估研究的第 1 波(Wave 1)与参与者 CBV 的 FV 水平合并,并限制在每天吸烟且包含在第 4 波(2016-2017 年)中的成年人中(n=371)。广义估计方程方法对 FV 和每天吸烟量(CPD)、戒烟兴趣、总尼古丁当量(TNE)和总 NNAL(烟草特异性致癌物质的生物标志物)的变化进行建模。FV 变化的定义为 CBV 变化导致 FV 增加或减少≥20%。二次分析使用基于 FV 变化的分析,该变化基于从<5%到>10%或从>10%到<5%的。
观察到切换到 FV 增加≥20%和从<5%到>10%的 CBV 的人群中 CPD 分别增加了 0.97 和 0.49,这表明了一个非显著的趋势。观察到 FV 减少≥20%和从>10%到<5%的人群中 CPD 分别减少了 1.31 和 1.97,这表明了一个非显著的趋势。戒烟兴趣和生物标志物的变化也没有意义,但有一个例外:与无变化相比,从>10%到<5% FV 减少的人群中 TNE 的减少更大(-8.51 与-0.25 nmol/mg 肌酐;p=0.0447)。
切换到 FV 较低的 CBV 似乎不会增加暴露,甚至可能会减少一些暴露。建议进行更多的调查以证实这些描述性发现。