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经环甲膜红外闪烁光引导行可视软镜经鼻气管插管:一项随机交叉研究。

Infrared flashing light through the cricothyroid membrane as guidance to awake intubation with a flexible bronchoscope: A randomised cross-over study.

机构信息

Department of Anaesthesiology, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Faculty of Medicine, Zurich University, Zurich, Switzerland.

出版信息

Acta Anaesthesiol Scand. 2023 Apr;67(4):432-439. doi: 10.1111/aas.14204. Epub 2023 Feb 2.

Abstract

BACKGROUND

In case of distorted airway anatomy, awake intubation with a flexible bronchoscope can be extremely difficult or even impossible. To facilitate this demanding procedure, an infrared flashing light source can be placed on the patient's neck superficial to the cricothyroid membrane. The light travels through the skin and tissue to the trachea, from where it can be registered by the advancing bronchoscope in the pharynx and seen as flashing white light on the monitor. We hypothesised that the application of this technique would allow more proximal and easier identification of the correct pathway to the trachea in patients with severe airway pathology.

METHODS

As part of awake intubation, patients underwent insertion of a flexible video bronchoscope via the mouth into the trachea. The procedure was performed twice, in random order in each patient, with and without the aid of the transcutaneous flashing infrared light. All insertions were video recorded to determine at which anatomical landmark within the airway the correct pathway was identified. The videos are accessible via this link: https://airwaymanagement.dk/infrared_comparative. The predefined landmarks were in successive order: oral cavity, oro-pharynx, tip of epiglottis, arytenoid cartilages, false cords, vocal cords and trachea, as well as the spaces between them.

RESULTS

Twenty-two patients had a total of 44 awake insertions with the flexible bronchoscope. The median anatomical level, at which correct identification of the trachea was obtained on the monitor, was, past the epiglottis, with the conventional technique, and at the level of the oropharynx, when using the infrared flashing light (p = .005). The time until the flashing light or the vocal cords were seen was 21 (22) S, mean (SD), and 48 (62) S, during the insertion with and without infrared flashing light activated, respectively (p = .005). Endoscopists rated it easier (p = .001) to recognise the entrance to the trachea in the infrared-group.

CONCLUSION

During awake intubation of patients with airway pathology, the application of trans-cricothyroid infrared flashing light to guide the insertion of a flexible bronchoscope significantly facilitated the recognition of the pathway into the trachea and the correct advancement of the flexible endoscope.

REGISTRATION OF CLINICAL TRIAL

NCT03930550.

摘要

背景

在气道解剖结构扭曲的情况下,使用柔性支气管镜进行清醒插管可能极其困难甚至不可能。为了方便这一具有挑战性的操作,可以将红外闪烁光源放置在甲状软骨膜浅面的患者颈部。光线穿过皮肤和组织到达气管,从那里可以被咽部的推进式支气管镜记录,并在监视器上看到闪烁的白光。我们假设,在气道病理学严重的患者中,应用这项技术可以使更靠近和更容易识别到通向气管的正确路径。

方法

作为清醒插管的一部分,患者经口将柔性视频支气管镜插入气管。该操作在每个患者中以随机顺序进行两次,一次在有和没有经皮红外闪烁光的情况下进行。所有插入均进行视频记录,以确定在气道的哪个解剖标志上识别出正确的路径。可以通过以下链接访问视频:https://airwaymanagement.dk/infrared_comparative。预定义的标志依次为:口腔、口咽、会厌尖端、杓状软骨、假声带、声带和气管,以及它们之间的空间。

结果

22 名患者共进行了 44 次清醒插入柔性支气管镜的操作。在监视器上正确识别气管的中位数解剖水平,在常规技术下是在会厌之后,而在使用红外闪烁光时是在口咽水平(p=0.005)。看到闪烁光或声带的时间分别为使用和不使用红外闪烁光时的 21(22)秒和 48(62)秒(p=0.005)。内镜医师认为在红外组中更容易识别气管入口(p=0.001)。

结论

在气道病理患者的清醒插管中,应用经甲状软骨红外闪烁光引导柔性支气管镜插入可显著促进对进入气管的路径的识别以及柔性内镜的正确推进。

临床试验注册

NCT03930550。

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