Hu Xiaoxiao, Wang Ke, Sun Mengya, Li Chang, Wang Huanjun, Guan Jian
Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No.58 Zhongshanerlu Road, Guangzhou, 510080, Guangdong, People's Republic of China.
Abdom Radiol (NY). 2023 Mar;48(3):1051-1061. doi: 10.1007/s00261-023-03812-5. Epub 2023 Jan 23.
To investigate the feasibility of quantitative MRI in the differentiation of bladder paraganglioma from bladder leiomyoma.
From 2014 to 2021, 11 patients with bladder paraganglioma and 14 patients with bladder leiomyoma confirmed by surgical pathology were retrospectively collected. All patients underwent multiparametric scanning with a 3.0 T MR system. Quantitative parameters including the SI-ratio on TWI between the solid component of tumours and piriformis, ADC value and E-rate of the solid component of tumours were assessed. Independent sample t test or Mann-Whitney U test was used to compare these parameters between the two groups. The diagnostic efficiency of the parameters was examined using ROC curve analysis and the DeLong test.
There were significant differences in SI-ratio on TWI (P < 0.001), ADC value (P = 0.002) and the E-rate (P = 0.040) between the paraganglioma group and the leiomyoma group. The cutoff value of SI-ratio on 3 leiomyoma was 1.241, and the AUC was 1.000 (0.858-1.000). The cutoff value of the ADC value was 0.979 × 10mm/s, and the AUC was 0.907 (0.717-0.987). The cutoff value of E-rate was 98.7%, and the AUC was 0.714 (0.495-0.878). The AUCs of the SI-ratio on TWI and ADC value were significantly higher than the E-rate AUC (P = 0.015 and 0.034, respectively).
Quantitative MRI can effectively distinguish bladder paraganglioma from bladder leiomyoma with the SI-ratio on TWI or ADC value.
探讨定量磁共振成像（MRI）鉴别膀胱副神经节瘤与膀胱平滑肌瘤的可行性。
回顾性收集2014年至2021年经手术病理证实的11例膀胱副神经节瘤患者和14例膀胱平滑肌瘤患者。所有患者均采用3.0 T MR系统进行多参数扫描。评估肿瘤实性成分与梨状肌之间TWI上的SI比值、肿瘤实性成分的表观扩散系数（ADC）值和增强率等定量参数。采用独立样本t检验或曼-惠特尼U检验比较两组间这些参数。利用ROC曲线分析和德龙检验检验参数的诊断效能。
副神经节瘤组与平滑肌瘤组在TWI上的SI比值（P＜0.001）、ADC值（P = 0.002）和增强率（P = 0.040）方面存在显著差异。3例平滑肌瘤的SI比值截断值为1.241，曲线下面积（AUC）为1.000（0.858 - 1.000）。ADC值的截断值为0.979×10⁻³mm²/s，AUC为0.907（0.717 - 0.987）。增强率的截断值为98.7%，AUC为0.714（0.495 - 0.878）。TWI上的SI比值和ADC值的AUC显著高于增强率的AUC（分别为P = 0.015和0.034）。
定量MRI可通过TWI上的SI比值或ADC值有效区分膀胱副神经节瘤与膀胱平滑肌瘤。
