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腹腔镜与开腹 Hartmann 术式回肠造口还纳术的对比:倾向评分匹配分析。

Laparoscopic versus open Hartmann reversal: a propensity score matching analysis.

机构信息

Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

出版信息

Int J Colorectal Dis. 2023 Jan 24;38(1):22. doi: 10.1007/s00384-023-04320-0.

Abstract

PURPOSE

The purpose of this study was to compare the short-term outcomes between laparoscopic Hartmann reversal (LHR) and open Hartmann reversal (OHR) in patients who had undergone Hartmann surgery for colorectal cancer (CRC).

METHODS

The patients who underwent Hartmann reversal (HR) at the First Affiliated Hospital of Chongqing Medical University from Jun 2013 to Jun 2022 were retrospectively enrolled. The LHR group and the OHR group were compared using propensity score matching (PSM) analysis.

RESULTS

A total of 89 patients who underwent Hartmann reversal (HR) were enrolled in this study. There were 48 (53.9%) patients in the LHR group and 41 (46.1%) patients in the OHR group. After 1:1 ratio PSM, no difference in baseline information remained (p > 0.05). There was no significant difference in operation time, blood loss, postoperative hospital stay, and postoperative complications (p > 0.05) before and after PSM. In the multivariable logistic regression analysis, pre-operative albumin < 42.0 g/L was an independent risk factor (p = 0.013 < 0.05, OR = 0.248, 95% CI = 0.083-0.741) for the HR-related complications; however, LHR/OHR was not a predictive risk factor (p = 0.663, OR = 1.250, 95% CI = 0.500-3.122).

CONCLUSION

Based on the current evidence, although there was no difference in short-term prognosis, LHR still had some advantages considering that it was less invasive to the patient.

摘要

目的

本研究旨在比较腹腔镜Hartmann 反转术(LHR)与开腹 Hartmann 反转术(OHR)治疗结直肠癌(CRC)行 Hartmann 手术后患者的短期疗效。

方法

回顾性分析 2013 年 6 月至 2022 年 6 月在重庆医科大学附属第一医院行 Hartmann 反转术(HR)的患者。采用倾向性评分匹配(PSM)分析比较 LHR 组和 OHR 组。

结果

本研究共纳入 89 例行 HR 的患者。其中 LHR 组 48 例(53.9%),OHR 组 41 例(46.1%)。1:1 比例 PSM 后,两组患者的基线资料无差异(p>0.05)。PSM 前后两组手术时间、术中出血量、术后住院时间及术后并发症比较,差异均无统计学意义(p>0.05)。多因素 logistic 回归分析显示,术前白蛋白<42.0 g/L 是 HR 相关并发症的独立危险因素(p=0.013<0.05,OR=0.248,95%CI=0.083-0.741),但 LHR/OHR 不是预测危险因素(p=0.663,OR=1.250,95%CI=0.500-3.122)。

结论

基于现有证据,尽管短期预后无差异,但考虑到对患者的创伤更小,LHR 仍具有一定优势。

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