Reniers J, Vranckx R, Ngantung W, Sugita E, Meheus A
Epidemiology and Community Medicine, University of Antwerp, Belgium.
J Trop Med Hyg. 1987 Oct;90(5):249-53.
In Bandung, West Java, 300 consecutive pregnant women were screened for hepatitis B virus (HBV) markers at a prenatal consultation. The prevalence of HBsAg and of anti-HBs/anti-HBc was 4.7% (14/300) and 35.6% (107/300) respectively, while 59.7% (179/300) was sero-negative. Prevalence of HBV markers increased significantly with both age and parity. Women with less schooling and a low socioeconomic class seemed to be at higher risk for HBV infection (HBV-markers prevalence of 49.3% (35/71) and 58.3% (21/36) respectively). Among employed women, the subgroup of school-teachers had a significantly higher HBV-markers prevalence of 54.8% (23/42), with a HBsAg carrier rate of 11.9% (5/42). This could indicate an important nonparenteral transmission of HBV in schools. The prevalence of HBeAg in HBsAg positive women was 64.3% (9/14). Based on historical data on perinatal HBV transmission, this would lead to a HBV carriership in 2.4 to 3.5% of all newborns. Possible strategies of prevention of HBV infection in newborns are briefly discussed.
在西爪哇省的万隆，300名连续的孕妇在产前咨询时接受了乙肝病毒（HBV）标志物筛查。HBsAg和抗-HBs/抗-HBc的流行率分别为4.7%（14/300）和35.6%（107/300），而59.7%（179/300）为血清学阴性。HBV标志物的流行率随年龄和产次显著增加。受教育程度较低且社会经济阶层较低的女性似乎感染HBV的风险更高（HBV标志物流行率分别为49.3%（35/71）和58.3%（21/36））。在就业女性中，教师亚组的HBV标志物流行率显著更高，为54.8%（23/42），HBsAg携带率为11.9%（5/42）。这可能表明学校中存在重要的HBV非肠道传播。HBsAg阳性女性中HBeAg的流行率为64.3%（9/14）。根据围产期HBV传播的历史数据，这将导致所有新生儿中有2.4%至3.5%成为HBV携带者。本文简要讨论了预防新生儿HBV感染的可能策略。
