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一名乳腺癌患者发生阿霉素延迟性心肌病:病例报告

Delayed doxorubicin induced cardiomyopathy in a breast cancer patient: A case report.

作者信息

Song David, Shabani Jawad, Jaiswal Vikash, Cagliostro Matthew, Rubinstein David, Alraies M Chadi

机构信息

Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Elmhurst Hospital Center, Queens, NY, USA.

Department of Research, Larkin Community Hospital, South Miami, FL, 33143, USA.

出版信息

Radiol Case Rep. 2023 Jan 13;18(3):1256-1260. doi: 10.1016/j.radcr.2022.12.048. eCollection 2023 Mar.

Abstract

Heart failure (HF) is a clinical syndrome with a wide spectrum of presentations and an even wider array of etiologies. Anthracyclines such as Doxorubicin, Daunorubicin, Idarubicin, and Epirubicin have demonstrated increased risk of HF with significant morbidity and mortality. We present an interesting case report of a patient with a history of breast cancer treated with Doxorubicin who presented with symptoms of HF who had a comprehensive evaluation that excluded the most common etiologies, narrowing our diagnosis to late onset doxorubicin induced HF with on-going recovery after initiation of guideline-directed medical therapy.

摘要

心力衰竭(HF)是一种临床表现多样、病因更为广泛的临床综合征。阿霉素、柔红霉素、伊达比星和表柔比星等蒽环类药物已显示出发生HF的风险增加,且具有显著的发病率和死亡率。我们报告了一例有趣的病例,该患者有乳腺癌病史,曾接受阿霉素治疗,出现了HF症状,经过全面评估排除了最常见的病因,将诊断范围缩小为迟发性阿霉素诱导的HF,在开始指南指导的药物治疗后病情正在恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31a9/9860264/1d6f143e0c5c/gr1.jpg

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