Yang Mei, Chen Mu, Gong Chang-Qi, Li Wei, Zhang Peng-Pai, Zhang Rui, Mo Bing-Feng, Ding Hui-Rong, Wang Qun-Shan, Lu Qiu-Fen, Sun Jian, Li Yi-Gang
Department of Cardiology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, 1665 Kongjiang Road, 200092 Shanghai, China.
Department of Nursing, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, 1665 Kongjiang Road, 200092 Shanghai, China.
Heliyon. 2023 Jan 3;9(1):e12662. doi: 10.1016/j.heliyon.2022.e12662. eCollection 2023 Jan.
Left atrial appendage (LAA) closure (LAAC) in atrial fibrillation (AF) patients with the reversed chicken-wing (RCW) LAA is challenging.
To elucidate the LAAC strategy of the RCW-LAA.
A total of 802 AF patients who were enrolled in the LAACablation registry for LAAC procedure were included, 55 of whom presented with the RCW-LAA. The WATCHMAN device was implanted using the standard protocol when the sheath depth was no less than the device depth (the simple group). For those with a sheath depth of less than the device depth (the complex group), device deployment was attempted with acceptable protrusion or after a repeated atrial transseptal puncture (re-ATP) at a more inferior and anterior position. The anatomical and procedural features were compared between groups and before and after the re-ATP.
The success rate of LAAC was significantly lower in patients with the RCW-LAA than with the other morphologies (92.7% vs. 98.8%, p = 0.001). Compared with the simple group, the complex group had shorter root depth and shorter neck length, and more LAAs in the complex group were at lower position (all p < 0.05). The sheath depth after the re-ATP was significantly greater than that before the re-ATP (18.8 ± 3.4 mm vs. 14.7 ± 2.6 mm, p < 0.001). For the patients who underwent re-ATP, the sheath went significantly deeper in successful procedures than in aborted procedures (19.7 ± 3.3 mm vs. 15.8 ± 1.8 mm, p = 0.040).
The anatomical features of the RCW-LAA were related to the complexity of the LAAC procedure. The re-ATP at an inferior and anterior location could increase the success rate of LAAC.
NCT03788941.
在患有反鸡翅样(RCW)左心耳(LAA)的心房颤动(AF)患者中进行左心耳封堵(LAAC)具有挑战性。
阐明RCW-LAA的LAAC策略。
共纳入802例因LAAC手术而登记在LAAC消融登记处的AF患者,其中55例表现为RCW-LAA。当鞘管深度不少于器械深度时,按照标准方案植入WATCHMAN器械(简单组)。对于鞘管深度小于器械深度的患者(复杂组),尝试在可接受的突出情况下或在更靠下和靠前的位置重复进行房间隔穿刺(re-ATP)后进行器械部署。比较两组之间以及re-ATP前后的解剖学和手术特征。
RCW-LAA患者的LAAC成功率显著低于其他形态的患者(92.7%对98.8%,p = 0.001)。与简单组相比,复杂组的根部深度较短、颈部长度较短,且复杂组中更多的LAA位于较低位置(所有p < 0.05)。re-ATP后的鞘管深度显著大于re-ATP前(18.8±3.4mm对14.7±2.6mm,p < 0.001)。对于接受re-ATP的患者,成功手术中的鞘管进入深度显著深于失败手术(19.7±3.3mm对15.8±1.8mm,p = 0.040)。
RCW-LAA的解剖特征与LAAC手术的复杂性相关。在靠下和靠前位置进行re-ATP可提高LAAC的成功率。
NCT03788941。