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在植入左心耳封堵装置时使用通用可操纵鞘管的首例人体经验。

First-in-Human Experience of Using a Universal Steerable Sheath in Implanting Left Atrial Appendage Closure Devices.

作者信息

Chang Sheng-Nan, Chiu Fu-Chun, Chen Jien-Jiun, Huang Pang-Shuo, Lin Ting-Tse, Cheng Hsiao-Liang, Tsai Chin-Feng, Wang Yi-Chih, Tsai Chia-Ti

机构信息

Division of Cardiology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital Yun-Ling Branch, Dou-Liu City, Taiwan.

Division of Cardiology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital Hsin-Chu Branch, Hsin-Chu City, Taiwan.

出版信息

JACC Asia. 2022 Nov 15;2(6):780-783. doi: 10.1016/j.jacasi.2022.08.003. eCollection 2022 Nov.

DOI:10.1016/j.jacasi.2022.08.003
PMID:36444320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9700041/
Abstract

Left atrial appendage (LAA) closure (LAAC) device implantation may be challenging in cases with difficult LAA anatomy. A deflectable sheath to approach multiple LAA positions may be helpful. We used a deflectable sheath to implant LAAC devices in 20 patients and included 60 cases using the standard sheaths for comparison. The procedures were successful in all patients without peri-procedural complications. After a median follow-up of 1.52 (IQR: 0.76-2.33) years, none of the patients in the deflectable sheath group had peri-device leak ≥3 mm and experienced thromboembolic stroke. In the standard sheath group, after follow-up of 2.03 (IQR: 0.87-3.19) years, 2 had peri-device leak ≥3 mm and 1 experienced thromboembolic stroke. We first proved the idea of using a universal steerable sheath for LAAC device implantation in difficult LAA anatomy, which also allows rapid switching of different LAAC devices.

摘要

在左心耳(LAA)解剖结构复杂的病例中,植入左心耳封堵(LAAC)装置可能具有挑战性。使用可弯曲鞘管到达多个LAA位置可能会有所帮助。我们使用可弯曲鞘管为20例患者植入LAAC装置,并纳入60例使用标准鞘管的病例作为对照。所有患者手术均成功,且无围手术期并发症。在中位随访1.52(四分位间距:0.76 - 2.33)年之后,可弯曲鞘管组中没有患者出现≥3 mm的装置周围渗漏,也没有发生血栓栓塞性卒中。在标准鞘管组中,随访2.03(四分位间距:0.87 - 3.19)年之后,有2例出现≥3 mm的装置周围渗漏,1例发生血栓栓塞性卒中。我们首次证实了在LAA解剖结构复杂的情况下使用通用可操纵鞘管植入LAAC装置的想法,这也允许快速切换不同的LAAC装置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/e9dd6aa96324/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/b4c8e8e0a9e5/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/403e41c63bfe/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/e9dd6aa96324/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/b4c8e8e0a9e5/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/403e41c63bfe/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0170/9700041/e9dd6aa96324/gr2.jpg

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本文引用的文献

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First-in-human experience of left atrial appendage occlusion with the steerable FuStar sheath.可操控FuStar鞘管用于左心耳封堵的人体首次经验。
J Interv Cardiol. 2018 Aug;31(4):532-537. doi: 10.1111/joic.12509. Epub 2018 Mar 26.
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C-reactive protein gene polymorphism predicts the risk of thromboembolic stroke in patients with atrial fibrillation: a more than 10-year prospective follow-up study.C-反应蛋白基因多态性预测心房颤动患者血栓栓塞性卒中的风险:一项超过 10 年的前瞻性随访研究。
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在二尖瓣经导管缘对缘修复术后使用可操纵输送鞘管实现左心耳封堵同轴对准:一例报告
Eur Heart J Case Rep. 2024 Jan 5;8(1):ytad592. doi: 10.1093/ehjcr/ytad592. eCollection 2024 Jan.
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