Mai Van Cuong, Li Di, Duan Hongwei
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 70 Nanyang Drive, 637457 Singapore.
Langmuir. 2023 Feb 7;39(5):1709-1718. doi: 10.1021/acs.langmuir.2c03227. Epub 2023 Jan 24.
Phenolic-compound-based functional coatings that allow for flexible modulation of chemical and surface properties have found widespread uses in a diverse range of biomedical applications from antibiofouling and antioxidation to bioimaging, therapeutics, and controlled drug delivery. It is imperative to understand the formation mechanism of phenolic coatings to fully meet the needs of their emerging applications in controlling the surface properties of biomaterials and medical devices. In this Perspective, we highlight the versatile chemical and self-assembly approaches to generate phenolic coatings with tailored surface properties and reactivities and also discuss how the surface properties and chemical reactivities impart functional materials for translational research.
基于酚类化合物的功能涂层能够灵活调节化学和表面性质，已在从抗生物污损、抗氧化到生物成像、治疗和可控药物递送等多种生物医学应用中得到广泛应用。为了充分满足其在控制生物材料和医疗设备表面性质方面新兴应用的需求，了解酚类涂层的形成机制至关重要。在这篇综述中，我们重点介绍了生成具有定制表面性质和反应活性的酚类涂层的多种化学和自组装方法，并讨论了表面性质和化学反应活性如何为转化研究赋予功能材料。
