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腹腔镜手术在高危急诊普通外科中可减少重症监护病房停留时间、住院时间和死亡率。

Laparoscopy in high-risk emergency general surgery reduces intensive care stay, length of stay and mortality.

机构信息

Department of Upper GI Surgery, Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth, PO3 6LY, UK.

出版信息

Langenbecks Arch Surg. 2023 Jan 24;408(1):62. doi: 10.1007/s00423-022-02744-w.


DOI:10.1007/s00423-022-02744-w
PMID:36692646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9872062/
Abstract

PURPOSE: Emergency general surgery patients undergoing laparoscopic surgery are at reduced risk of mortality and may require reduced length of critical care stay. This study investigated the effect of laparoscopy on high-risk patients' post-operative care requirements. METHODS: Data were retrieved for all patients entered into the NELA database between 2013 and 2018. Only high-risk surgical patients (P-POSSUM predicted mortality risk of ≥ 5%) were included. Patients undergoing laparoscopic and open emergency general surgical procedures were compared using a propensity score weighting approach. Outcome measures included total length of critical care (level 3) stay, overall length of stay and inpatient mortality. RESULTS: A total of 66,517 high-risk patients received emergency major abdominal surgery. A laparoscopic procedure was attempted in 6998 (10.5%); of these, the procedure was competed laparoscopically in 3492 (49.9%) and converted to open in 3506 (50.1%). Following inverse probability treatment weighting adjustment for patient disease and treatment characteristics, high-risk patients undergoing laparoscopic surgery had a shorter median ICU stay (1 day vs 2 days p < 0.001), overall hospital length of stay (11 days vs 14 days p < 0.001) and a lower inpatient mortality (16.0% vs 18.8%, p < 0.001). They were also less likely to have a prolonged ICU stay with an OR of 0.78 (95% CI 0.74-0.83, p < 0.001). CONCLUSION: The results of this study suggest that in patients at high risk of post-operative mortality, laparoscopic emergency bowel surgery leads to a reduced length of critical care stay, overall length of stay and inpatient mortality compared to traditional laparotomy.

摘要

目的:接受腹腔镜手术的急诊普通外科患者的死亡率较低,可能需要缩短重症监护的住院时间。本研究调查了腹腔镜手术对高危患者术后护理需求的影响。

方法:检索了 2013 年至 2018 年期间纳入 NELA 数据库的所有患者的数据。仅纳入高危手术患者(P-POSSUM 预测死亡率≥5%)。使用倾向评分加权方法比较腹腔镜和开放急诊普通外科手术的患者。观察指标包括重症监护(3 级)总住院时间、总住院时间和住院死亡率。

结果:共有 66517 例高危患者接受了紧急大腹部手术。尝试了腹腔镜手术 6998 例(10.5%);其中,3492 例(49.9%)完成了腹腔镜手术,3506 例(50.1%)转为开腹手术。对患者疾病和治疗特征进行逆概率治疗加权调整后,接受腹腔镜手术的高危患者 ICU 住院时间中位数更短(1 天比 2 天,p<0.001)、总住院时间更短(11 天比 14 天,p<0.001)、住院死亡率更低(16.0%比 18.8%,p<0.001)。他们也不太可能有较长的 ICU 住院时间,优势比为 0.78(95%CI 0.74-0.83,p<0.001)。

结论:本研究结果表明,对于术后死亡率高的患者,与传统剖腹手术相比,腹腔镜急诊肠手术可缩短重症监护住院时间、总住院时间和住院死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07fa/9872062/4a598bd4d10d/423_2022_2744_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07fa/9872062/4a598bd4d10d/423_2022_2744_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07fa/9872062/4a598bd4d10d/423_2022_2744_Fig1_HTML.jpg

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Laparoscopy in high-risk emergency general surgery reduces intensive care stay, length of stay and mortality.

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[2]
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[3]
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[4]
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引用本文的文献

[1]
Postoperative ileus after emergency surgery for acute bowel obstruction: a case-control study of predictors and impact on recovery.

Langenbecks Arch Surg. 2025-9-1

[2]
Trends in Clinical Outcomes After Major Emergency Abdominal Surgery in Denmark, Data From 2002-2022.

JAMA Surg. 2025-4-23

[3]
Minimally invasive approach to peritonitis from left colonic perforation: a retrospective multicenter observational study.

Surg Endosc. 2025-4

[4]
Open versus laparoscopic completion cholecystectomy in patients with previous open partial cholecystectomy: a retrospective comparative study.

Ann Med Surg (Lond). 2024-8-6

[5]
Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago.

World J Emerg Surg. 2024-4-16

[6]
European society for trauma and emergency surgery member-identified research priorities in emergency surgery: a roadmap for future clinical research opportunities.

Eur J Trauma Emerg Surg. 2024-4

[7]
Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.

World J Emerg Surg. 2023-12-8

本文引用的文献

[1]
Feasibility of laparoscopy and factors associated with conversion to open in minimally invasive emergency major abdominal surgery: population database analysis.

Surg Endosc. 2022-6

[2]
Sarcopenia and Myosteatosis Predict Adverse Outcomes After Emergency Laparotomy: A Multi-center Observational Cohort Study.

Ann Surg. 2022-6-1

[3]
A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery.

Br J Surg. 2021-8-19

[4]
The laparoscopy in emergency general surgery (LEGS) study: a questionnaire survey of UK practice.

Ann R Coll Surg Engl. 2021-2

[5]
The long-term effects of prolonged intensive care stay postcardiac surgery.

J Card Surg. 2020-11

[6]
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World J Emerg Surg. 2020-5-7

[7]
Perforated and bleeding peptic ulcer: WSES guidelines.

World J Emerg Surg. 2020

[8]
Laparoscopic Compared With Open Resection for Colorectal Cancer and Long-term Incidence of Adhesional Intestinal Obstruction and Incisional Hernia: A Systematic Review and Meta-analysis.

Dis Colon Rectum. 2020-1

[9]
Laparoscopic versus open adhesiolysis for adhesive small bowel obstruction (LASSO): an international, multicentre, randomised, open-label trial.

Lancet Gastroenterol Hepatol. 2019-2-12

[10]
The role of emergency laparoscopic colectomy for complicated sigmoid diverticulits: A systematic review and meta-analysis.

Surgeon. 2018-10-9

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