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心脏手术后长时间重症监护的长期影响。

The long-term effects of prolonged intensive care stay postcardiac surgery.

机构信息

School of Health Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.

Specialist Surgery Division, University College London Hospital, University College London Hospitals NHS Trust, London, UK.

出版信息

J Card Surg. 2020 Nov;35(11):3099-3107. doi: 10.1111/jocs.14963. Epub 2020 Aug 25.

Abstract

OBJECTIVES

Short-term outcomes for those with a prolonged length of stay (LOS) in intensive care (ITU) following cardiac surgery are poor, with higher rates of in-hospital mortality and morbidity. Consequently, discharge from hospital has been considered the key measure of success. However, there has been a shift towards long-term outcomes, functional recovery and quality of life (QoL) as measures of surgical quality. The aim of this review is to compare and critique the findings of multiple studies to determine the long-term effects of prolonged ITU stay postcardiac surgery.

METHODS

A computerized literature search of CINAHL, EMBASE and Google Scholar databases, based on keywords "long-term effects," "prolonged ITU stay," "cardiac surgery," with rigorous CASP critique was undertaken.

RESULTS

The search yielded 12 papers meeting the inclusion criteria, with eight retrospective and four prospective studies. Eight of these 12 papers identified inferior long-term survival or higher mortality rates for those who had prolonged LOS in ITU in comparison to "normal" LOS or a control. The greatest burden of mortality was 6 months to 1 year postdischarge. Three papers found that quality of life was adversely affected or worse for those who had experienced prolonged LOS in ITU.

CONCLUSIONS

Further research is required to provide better quality evidence into QoL, following prolonged stay in ICU postcardiac surgery. The evidence reviewed suggests that the risk of mortality in this demographic of patients is higher, especially within the first year and, therefore, more frequent medical surveillance of these patients is recommended.

摘要

目的

心脏手术后在重症监护病房(ICU)中停留时间延长(LOS)的患者短期预后较差,住院死亡率和发病率较高。因此,出院被认为是成功的关键衡量标准。然而,人们已经将长期预后、功能恢复和生活质量(QoL)作为手术质量的衡量标准。本综述的目的是比较和评价多项研究的结果,以确定心脏手术后 ICU 停留时间延长的长期影响。

方法

根据关键词“长期影响”、“延长 ICU 停留时间”、“心脏手术”,对 CINAHL、EMBASE 和 Google Scholar 数据库进行计算机文献检索,并进行严格的 CASP 评估。

结果

搜索结果共 12 篇符合纳入标准的论文,其中 8 篇为回顾性研究,4 篇为前瞻性研究。这 12 篇论文中有 8 篇认为与“正常” LOS 或对照组相比,ICU 中 LOS 延长的患者长期生存率较低或死亡率较高。出院后 6 个月至 1 年内的死亡率最高。有 3 篇论文发现,ICU 中 LOS 延长的患者生活质量受到不利影响或更差。

结论

需要进一步研究,以提供更好质量的证据,了解心脏手术后 ICU 长时间停留对 QoL 的影响。综述中的证据表明,这些患者群体的死亡率风险更高,尤其是在第一年,因此建议更频繁地对这些患者进行医疗监测。

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