比较智能手机虚拟现实暴露准备与常规护理对6至14岁接受磁共振成像儿童的影响：一项多中心、观察者盲法、随机对照试验方案

Comparing Smartphone Virtual Reality Exposure Preparation to Care as Usual in Children Aged 6 to 14 Years Undergoing Magnetic Resonance Imaging: Protocol for a Multicenter, Observer-Blinded, Randomized Controlled Trial.

作者信息

van Spaendonck Zita, Leeuwenburgh Koen Pieter, Dremmen Marjolein, van Schuppen Joost, Starreveld Daniëlle, Dierckx Bram, Legerstee Jeroen S

机构信息

Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center Sophia Children's Hospital, Rotterdam, Netherlands.

Department of Radiology, Erasmus University Medical Center Sophia Children's Hospital, Rotterdam, Netherlands.

出版信息

JMIR Res Protoc. 2023 Jan 24;12:e41080. doi: 10.2196/41080.

DOI:10.2196/41080

PMID:36692931

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9906306/

Abstract

BACKGROUND

A magnetic resonance imaging (MRI) procedure can cause preprocedural and periprocedural anxiety in children. Psychosocial interventions are used to prepare children for the procedure to alleviate anxiety, but these interventions are time-consuming and costly, limiting their clinical use. Virtual reality (VR) is a promising way to overcome these limitations in the preparation of children before an MRI scan.

OBJECTIVE

The objective of this study is (1) to develop a VR smartphone intervention to prepare children at home for an MRI procedure; and (2) to examine the effect of the VR intervention in a randomized controlled trial, in which the VR intervention will be compared to care as usual (CAU). CAU involves an information letter about an MRI examination. The primary outcome is the child's procedural anxiety during the MRI procedure. Secondary outcomes include preprocedural anxiety and parental anxiety. We hypothesize that the VR preparation will result in a higher reduction of the periprocedural anxiety of both parents and children as compared to CAU.

METHODS

The VR intervention provides a highly realistic and child-friendly representation of an MRI environment. In this randomized controlled trial, 128 children (aged 6 to 14 years) undergoing an MRI scan will be randomly allocated to the VR intervention or CAU. Children in the VR intervention will receive a log-in code for the VR app and are sent cardboard VR glasses.

RESULTS

The VR smartphone preparation app was developed in 2020. The recruitment of participants is expected to be completed in December 2022. Data will be analyzed, and scientific papers will be submitted for publication in 2023.

CONCLUSIONS

The VR smartphone app is expected to significantly reduce pre- and periprocedural anxiety in pediatric patients undergoing an MRI scan. The VR app offers a realistic and child-friendly experience that can contribute to modern care. A smartphone version of the VR app has the advantage that children, and potentially their parents, can get habituated to the VR environment and noises in their own home environment and can do this VR MRI preparation as often and as long as needed.

TRIAL REGISTRATION

ISRCTN Registry ISRCTN20976625; https://www.isrctn.com/ISRCTN20976625.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/41080.

摘要

背景

磁共振成像（MRI）检查可能会导致儿童在检查前和检查过程中出现焦虑情绪。心理社会干预措施用于帮助儿童为检查做好准备以减轻焦虑，但这些干预措施耗时且成本高，限制了它们的临床应用。虚拟现实（VR）是一种很有前景的方法，可以克服在为儿童进行MRI扫描前准备工作中的这些限制。

目的

本研究的目的是：（1）开发一款VR智能手机应用程序，让儿童在家中为MRI检查做好准备；（2）在一项随机对照试验中检验VR干预的效果，将VR干预与常规护理（CAU）进行比较。CAU包括一封关于MRI检查的信息信。主要结局是儿童在MRI检查过程中的操作焦虑。次要结局包括检查前焦虑和家长焦虑。我们假设与CAU相比，VR准备措施将能更大程度地降低家长和儿童在检查过程中的焦虑。

方法

VR干预提供了一个高度逼真且对儿童友好的MRI环境呈现。在这项随机对照试验中，128名接受MRI扫描的儿童（6至14岁）将被随机分配到VR干预组或CAU组。VR干预组的儿童将收到VR应用程序的登录代码，并会收到纸质VR眼镜。

结果

VR智能手机准备应用程序于2020年开发完成。预计参与者招募工作将于2022年12月完成。将对数据进行分析，并在2023年提交科学论文以供发表。

结论

VR智能手机应用程序预计能显著降低接受MRI扫描的儿科患者在检查前和检查过程中的焦虑。VR应用程序提供了一种逼真且对儿童友好的体验，有助于现代医疗护理。VR应用程序的智能手机版本具有这样的优势，即儿童以及他们的家长可以在自己家中的环境中适应VR环境和噪音，并且可以根据需要多次且长时间地进行这种VR MRI准备。