Yamada S, Hoshi A, Takai Y, Hoshino F, Mochizuki Y, Kanehira C, Kaneta K
Dept. of Radiology, Tohoku Univ. School of Med.
Gan No Rinsho. 1987 Aug;33(10):1189-92.
409 patients whose spinal cord were irradiated over 30 Gy with conventionally fractionated method were surveyed to study the relation between the dose of spinal cord and the incidence of radiation myelitis. Radiation myelitis was observed in 26 cases including 3 transverse myelitis ones. 5 year incidences of transverse myelitis calculated with life table method were approximately 0% at 40 Gy, 5% at 50 Gy, 10% at 60 Gy and 20% at 70 Gy. The radiation tolerance dose of the spinal cord was considered to be 50 Gy.
对409例采用常规分割方法脊髓照射剂量超过30 Gy的患者进行调查,以研究脊髓剂量与放射性脊髓炎发生率之间的关系。观察到26例放射性脊髓炎,其中包括3例横贯性脊髓炎。采用寿命表法计算的横贯性脊髓炎5年发生率在40 Gy时约为0%,50 Gy时为5%,60 Gy时为10%,70 Gy时为20%。脊髓的放射耐受剂量被认为是50 Gy。