Gopalakrishnakone P
Department of Anatomy, Faculty of Medicine, National University of Singapore, Kent Ridge.
Jpn J Exp Med. 1987 Apr;57(2):93-102.
Rabbits affected by a neuromuscular disorder have been observed by light and electron microscopy. The presynaptic portion of the neuromuscular junction showed many changes such as depletion or reduction in synaptic vesicle population, degenerative changes in mitochondria. Intra-muscular axons showed few changes such as disorientation and ramification of neurofilaments. The muscle fibres showed some degenerated fibres and increased collagen around the muscle fibres. Intramuscular blood capillaries also showed proliferation of endothelial cells.
通过光学显微镜和电子显微镜观察了患有神经肌肉疾病的兔子。神经肌肉接头的突触前部分表现出许多变化，如突触小泡数量减少或耗竭、线粒体退行性变化。肌内轴突显示出一些变化，如神经丝排列紊乱和分支。肌纤维显示出一些退化的纤维，并且肌纤维周围的胶原增加。肌内毛细血管也显示出内皮细胞的增殖。
