Department of Medicine, University Hospital Zurich, Zürich, Switzerland.
NIHR King's Clinical Research Facility, King's College London, London, United Kingdom.
Cephalalgia. 2023 Jan;43(1):3331024221133383. doi: 10.1177/03331024221133383.
While migraine and cluster headache share some clinical features and therapies, they differ considerably in the frequency and duration of the headache, as well as the inter-attack, or inter-bout, pathophysiology. Neither is fully understood, with their shared pathways being of interest.
Five patients for whom it was difficult to distinguish migraine from cluster headache are presented. They had aspects of their phenotypes, which could be attributed to both disorders. Each patient was thoroughly examined, excluding secondary causes of headache, and had been treated with a number of medicines.
A correct diagnosis is key to the appropriate treatment approach. Especially, if treatment is not successful for the suspected headache type, and enlargement of the diagnostic and therapeutic range, respectively, should be evaluated. Whether in such settings there is shared or different pathophysiology can only be speculated upon.
偏头痛和丛集性头痛虽有一些临床特征和治疗方法相同，但头痛的频率和持续时间、发作间期或发作间歇期的病理生理学却有很大不同。两者都尚未完全被了解，它们的共同途径是研究的重点。
本文介绍了 5 例偏头痛和丛集性头痛难以鉴别的患者。他们的表型存在某些方面，可以归因于这两种疾病。每位患者都经过了彻底检查，排除了头痛的继发性原因，并接受了多种药物治疗。
正确的诊断是适当治疗方法的关键。特别是，如果疑似头痛类型的治疗不成功，应分别评估扩大诊断和治疗范围。在这种情况下，是否存在共同或不同的病理生理学只能推测。
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