Bakhshaee Mehdi, Teimouri Yeganeh, Jabbari Azad Farahzad, Yousefi Razieh, Parian Mahmoud, Berenji Fariba
Sinus and Surgical Endoscopic Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Allergy Research center, School of Medicine Mashhad University of Medical Sciences, Mashhad, Iran.
Iran J Parasitol. 2022 Oct-Dec;17(4):583-588. doi: 10.18502/ijpa.v17i4.11286.
Allergic rhinitis (AR) is one of the most common allergic diseases triggered by indoor and outdoor allergens. Certain arthropods, such as mites and cockroaches, contain protozoa like in their intestines to help with digestion that may have some role in AR. We aimed to determine the frequency of in nasal smears of patients with AR in comparison with healthy controls.
In this prospective cross-sectional study (March 2015-March 2016), 36 patients with a clinical presentation of AR (with a positive prick test including mites) and 34 normal controls were included at ear, nose, and throat (ENT) clinic at Imam Reza Hospital of Mashhad, Iran. Nasal secretions were evaluated to examine presence of in the patients and control group by direct method. Diagnosis of was based on microscopic observation both on direct smear and Giemsa stained specimens.
Patients with AR had a higher frequency of in their nasal smears than the control group (25% vs. 2.9%) (=0.001).
We found more frequently in the nasal secretion of AR patients compared with healthy subjects; this protozoon may have some role in this condition. However, the relationship between and AR requires further studies to allow a greater understanding.
变应性鼻炎（AR）是由室内和室外过敏原引发的最常见的变应性疾病之一。某些节肢动物，如螨虫和蟑螂，其肠道内含有有助于消化的原生动物，这可能在AR中发挥一定作用。我们旨在确定AR患者鼻涂片中原生动物的频率，并与健康对照进行比较。
在这项前瞻性横断面研究（2015年3月至2016年3月）中，伊朗马什哈德伊玛目礼萨医院耳鼻喉科门诊纳入了36例有AR临床表现（点刺试验阳性，包括螨虫）的患者和34例正常对照。通过直接法评估鼻分泌物，以检查患者和对照组中原生动物的存在情况。原生动物的诊断基于直接涂片和吉姆萨染色标本的显微镜观察。
AR患者鼻涂片中的原生动物频率高于对照组（25%对2.9%）（P=0.001）。
我们发现与健康受试者相比，AR患者鼻分泌物中原生动物更常见；这种原生动物可能在这种疾病中发挥一定作用。然而，原生动物与AR之间的关系需要进一步研究以加深理解。
