Del Brutto Oscar H, Mera Robertino M, Recalde Bettsy Y, Rumbea Denisse A, Sedler Mark J
School of Medicine and Research Center, Universidad Espíritu Santo-Ecuador, Samborondón, Ecuador.
Urbanización Toscana, Apt 3H, Km 4.5 vía Puntilla-Samborondón, 092301, Samborondón, Ecuador.
Eur J Nutr. 2023 Apr;62(3):1527-1533. doi: 10.1007/s00394-023-03093-0. Epub 2023 Jan 25.
To assess the relationship between dietary oily fish intake and all-cause mortality in a population of frequent fish consumers of Amerindian ancestry living in rural Ecuador.
Individuals aged ≥ 40 years enrolled in the prospective population-based Atahualpa Project cohort received annual questionnaires to estimate their dietary oily fish intake. Only fish served broiled or cooked in the soup were included for analysis. Poisson regression and Cox-proportional hazards models adjusted for demographics, education level and cardiovascular risk factors were obtained to estimate mortality risk according to the amount of oily fish intake stratified in tertiles.
Analysis included 909 individuals (mean age: 55.1 ± 12.8 years) followed by a median of 7.5 ± 3 years. Mean oily fish intake was 9.4 ± 5.7 servings per week. A total of 142 (16%) individuals died during the follow-up. The mortality rate for individuals in the first tertile de oily fish intake (0.0-6.29 servings) was 2.87 per 100 person-years, which decreased to 1.78 for those in the third tertile (10.59-35.0 servings). An adjusted Cox-proportional hazards model showed that individuals allocated to the second (HR 0.61; 95% CI 0.41-0.92) and third (HR 0.60; 95% CI 0.40-0.91) tertiles of dietary oily fish intake had significantly lower mortality risk than those in the first tertile.
Sustained oily fish intake of more than six servings per week reduces mortality risk in middle-aged and older adults of Amerindian ancestry.
评估厄瓜多尔农村地区美洲印第安人后裔这一经常食用鱼类人群的膳食油性鱼类摄入量与全因死亡率之间的关系。
参加基于人群的前瞻性阿塔瓦尔帕项目队列研究的年龄≥40岁的个体每年接受问卷调查，以估计其膳食油性鱼类摄入量。仅将烤或煮汤食用的鱼类纳入分析。根据按三分位数分层的油性鱼类摄入量，采用泊松回归和经人口统计学、教育水平及心血管危险因素调整的Cox比例风险模型来估计死亡风险。
分析纳入909名个体（平均年龄：55.1±12.8岁），随访时间中位数为7.5±3年。平均每周油性鱼类摄入量为9.4±5.7份。随访期间共有142名（16%）个体死亡。油性鱼类摄入量处于第一三分位数（0.0 - 6.29份）的个体死亡率为每100人年2.87例，而处于第三三分位数（10.59 - 35.0份）的个体死亡率降至1.78例。经调整的Cox比例风险模型显示，膳食油性鱼类摄入量处于第二（风险比0.61；95%置信区间0.41 - 0.92）和第三（风险比0.60；95%置信区间0.40 - 0.91）三分位数的个体死亡风险显著低于第一三分位数的个体。
每周持续摄入超过六份油性鱼类可降低美洲印第安人后裔中老年人的死亡风险。
