Xie Siqi, Zhao Cheng, Shen Jiabin, Wei Jing, Liu Haiquan, Pan Yingjie, Zhao Yong, Zhu Yongheng
College of Food Science and Technology, Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Storage and Preservation (Shanghai), Ministry of Agriculture and Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation Shanghai Ocean University, Shanghai 201306, China.
Institute of Analytical Chemistry and Instrument for Life Science, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.
ACS Sens. 2023 Feb 24;8(2):728-738. doi: 10.1021/acssensors.2c02257. Epub 2023 Jan 25.
, which is abundant in environment, can lead to many kinds of serious illnesses and even death. Nowadays, indirectly detecting the metabolite biomarker of , 3-hydroxy-2-butanone, has been verified to be an effective way to evaluate the contamination of . However, this detection approach is still limited by sensitivity, selectivity, and ppb-level detection limit. Herein, low-cost and highly sensitive and selective 3-hydroxy-2-butanone sensors have been proposed based on the bimetallic AuPd decorated hierarchical flower-like WO nanospheres. Notably, the 1.0 wt % AuPd-WO based sensors displayed the highest sensitivity (/ = 84 @ 1 ppm) at 250 °C. In addition, the sensors showed outstanding selectivity, rapid response/recovery (8/4 s @ 10 ppm), and low detection limit (100 ppb). Furthermore, the evaluation of with high sensitivity and specificity has been achieved using 1.0 wt % AuPd-WO based sensors. Such a marvelous sensing performance benefits from the synergistic effect of bimetallic AuPd nanoparticles, which lead to thicker electron depletion layer and increased adsorbed oxygen species. Meanwhile, the unique hierarchical nanostructure of the flower-like WO nanospheres benefits the gas-sensing performance. The AuPd-WO nanosphere-based sensors exhibit a particular and highly selective method to detect 3-hydroxy-2-butanone, foreseeing a feasible route for the rapid and nondestructive evaluation of foodborne pathogens.
在环境中含量丰富，可导致多种严重疾病甚至死亡。如今，间接检测其代谢物生物标志物3-羟基-2-丁酮已被证实是评估其污染的有效方法。然而，这种检测方法仍受灵敏度、选择性和十亿分之一级检测限的限制。在此，基于双金属AuPd修饰的分级花状WO纳米球，提出了低成本、高灵敏度和选择性的3-羟基-2-丁酮传感器。值得注意的是，基于1.0 wt% AuPd-WO的传感器在250℃时显示出最高灵敏度（/ = 84 @ 1 ppm）。此外，该传感器具有出色的选择性、快速响应/恢复（10 ppm时为8/4 s）和低检测限（100 ppb）。此外，使用基于1.0 wt% AuPd-WO的传感器实现了对的高灵敏度和特异性评估。这种出色的传感性能得益于双金属AuPd纳米颗粒的协同效应，这导致更厚的电子耗尽层和增加的吸附氧物种。同时，花状WO纳米球独特的分级纳米结构有利于气敏性能。基于AuPd-WO纳米球的传感器展示了一种特殊且高度选择性的检测3-羟基-2-丁酮的方法，为食源性病原体的快速无损评估预见了一条可行途径。
