Müller J H, Waigand J, Schuldt H H, Hölzer D H
Z Urol Nephrol. 1978 Oct;71(10):673-8.
Which consequences result from these experimental results from practice? In the acute angiography in postoperative functional distrubance after transplantation of a human kidney is at first probably always to be reckoned with a rejection process, though this immunological process by no means must be in the foreground of the causal connection of several pathogenetic factors. Therefore, in our opinion it would then be assumed an ischaemia-conditioned cell damage of the tubulus by a longer lasting prefinal circulatory depression or due to a not optimal preservation, when there is in the angiogramme a clear discrepancy to the severity of the postoperative functional distrubance, i.e. when angiographically exists only a slight cortical ischaemia in an otherwise good arterial filling picture and a widely normal capillary filling phase.
这些来自实践的实验结果会产生哪些后果呢?在人体肾脏移植术后功能障碍的急性血管造影中,起初可能总是要考虑到排斥反应过程,尽管这个免疫过程绝不一定处于多种致病因素因果关系的首要位置。因此,我们认为,当血管造影显示与术后功能障碍的严重程度存在明显差异时,即在动脉充盈良好、毛细血管充盈期基本正常的情况下,血管造影仅显示轻微的皮质缺血,那么就可以假定肾小管存在缺血性条件性细胞损伤,这是由于较长时间的终末循环抑制或保存不佳所致。