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[实验性肾缺血及肾同种移植后的血管变化(动物实验性血管造影研究)]

[Vascular changes in experimental renal ischemia and after renal homotransplantation (experimental angiographic study on animals)].

作者信息

Müller J H, Waigand J, Schuldt H H, Hölzer D H

出版信息

Z Urol Nephrol. 1978 Oct;71(10):673-8.

PMID:366969
Abstract

Which consequences result from these experimental results from practice? In the acute angiography in postoperative functional distrubance after transplantation of a human kidney is at first probably always to be reckoned with a rejection process, though this immunological process by no means must be in the foreground of the causal connection of several pathogenetic factors. Therefore, in our opinion it would then be assumed an ischaemia-conditioned cell damage of the tubulus by a longer lasting prefinal circulatory depression or due to a not optimal preservation, when there is in the angiogramme a clear discrepancy to the severity of the postoperative functional distrubance, i.e. when angiographically exists only a slight cortical ischaemia in an otherwise good arterial filling picture and a widely normal capillary filling phase.

摘要

这些来自实践的实验结果会产生哪些后果呢?在人体肾脏移植术后功能障碍的急性血管造影中,起初可能总是要考虑到排斥反应过程,尽管这个免疫过程绝不一定处于多种致病因素因果关系的首要位置。因此,我们认为,当血管造影显示与术后功能障碍的严重程度存在明显差异时,即在动脉充盈良好、毛细血管充盈期基本正常的情况下,血管造影仅显示轻微的皮质缺血,那么就可以假定肾小管存在缺血性条件性细胞损伤,这是由于较长时间的终末循环抑制或保存不佳所致。

相似文献

1
[Vascular changes in experimental renal ischemia and after renal homotransplantation (experimental angiographic study on animals)].[实验性肾缺血及肾同种移植后的血管变化(动物实验性血管造影研究)]
Z Urol Nephrol. 1978 Oct;71(10):673-8.
2
[Quantitative angiographic studies for the differential diagnosis of early acute kidney failure of ischemic and rejection-damaged grafts].[定量血管造影研究用于缺血性和排斥损伤移植物早期急性肾衰竭的鉴别诊断]
Z Urol Nephrol. 1979 Oct;72(10):715-22.
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[Angiographic kidney changes following homotransplantation in animal experiments].[动物实验中同种移植后的血管造影肾脏变化]
Z Urol Nephrol. 1971 Apr;64(4):295-304.
4
Angiographic evaluation of machine perfused kidneys.机器灌注肾脏的血管造影评估
Urol Res. 1975 Oct 29;3(3):123-7. doi: 10.1007/BF00256033.
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Early acute rejection in renal homotransplantation. Angiographic-pathologic correlation.肾同种移植早期急性排斥反应。血管造影与病理的相关性。
J Can Assoc Radiol. 1977 Mar;28(1):12-6.
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[Flow volume-velocity relationship in the circulation of acutely failing kidney transplants (experimental study)].[急性肾功能衰竭肾移植循环中的流量-速度关系(实验研究)]
Z Exp Chir. 1979;12(6):346-52.
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[Renal perfusion during experimental hyper-acute rejection. 133-xenon perfusion compared with microscopy and angiography (author's transl)].实验性超急性排斥反应期间的肾灌注。133-氙灌注与显微镜检查及血管造影术的比较(作者译)
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Angiography of renal transplant.
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[Angiographic studies on the blood flow in renal grafts in relation to vascular filling after short-term extracorporeal perfusion. I. Redistribution of the renal circulation immediately after release of the blood flow].[短期体外灌注后肾移植血管血流与血管充盈相关性的血管造影研究。I. 血流恢复后立即出现的肾循环再分布]
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Gamma-glutamyl transpeptidase. A sensitive indicator of renal ischaemic injury in experimental animals and renal homograft rejection in man.γ-谷氨酰转肽酶。实验动物肾缺血性损伤及人类肾移植排斥反应的敏感指标。
Ann R Coll Surg Engl. 1975 Nov;57(5):248-61.