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关于与纳米团簇相互作用的蛋白质的开放性问题。

Open questions on proteins interacting with nanoclusters.

作者信息

Antoine Rodolphe, Maysinger Dusica, Sancey Lucie, Bonačić-Koutecký Vlasta

机构信息

Institut Lumière Matière UMR 5306, Université Claude Bernard Lyon 1, CNRS, Univ Lyon, F- 69100, Villeurbanne, France.

Department of Pharmacology & Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.

出版信息

Commun Chem. 2022 Apr 6;5(1):47. doi: 10.1038/s42004-022-00665-9.

DOI:10.1038/s42004-022-00665-9
PMID:36697869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9814327/
Abstract

Interfacing ultrasmall metal nanoclusters (NCs) with proteins can present a dual opportunity: proteins can be used for protecting NCs, and the surface ligands of NCs may interact with proteins. Here, the authors identify and discuss remaining open questions surrounding the bio-NC interface that call for future research efforts.

摘要

将超小型金属纳米团簇（NCs）与蛋白质结合可带来双重机遇：蛋白质可用于保护纳米团簇，且纳米团簇的表面配体可能与蛋白质相互作用。在此，作者识别并讨论了围绕生物纳米团簇界面仍未解决的开放性问题，这些问题需要未来的研究努力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/9814327/b71a022ad3a5/42004_2022_665_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/9814327/e956282f3cc1/42004_2022_665_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/9814327/b71a022ad3a5/42004_2022_665_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/9814327/e956282f3cc1/42004_2022_665_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8301/9814327/b71a022ad3a5/42004_2022_665_Fig2_HTML.jpg

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引用本文的文献

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本文引用的文献

[1]
Functionalized Au nanoclusters as luminescent probes for protein carbonylation detection.

Commun Chem. 2021-5-14

[2]
Tailoring the NIR-II Photoluminescence of Single Thiolated Au Nanoclusters by Selective Binding to Proteins.

Chemistry. 2022-7-11

[3]
Insights into the Impact of Gold Nanoclusters AuSG on Human Microglia.

ACS Chem Neurosci. 2022-2-16

[4]
Size and ligand effects of gold nanoclusters in alteration of organellar state and translocation of transcription factors in human primary astrocytes.

Nanoscale. 2021-2-11

[5]
Ligand shell size effects on one- and two-photon excitation fluorescence of zwitterion functionalized gold nanoclusters.

Phys Chem Chem Phys. 2019-10-28

[6]
Golden Opportunity: A Clickable Azide-Functionalized [Au(SR)] Nanocluster Platform for Interfacial Surface Modifications.

J Am Chem Soc. 2019-7-23

[7]
Enhanced two-photon absorption of ligated silver and gold nanoclusters: theoretical and experimental assessments.

Nanoscale. 2019-7-14

[8]
Gold nanoclusters as a contrast agent for image-guided surgery of head and neck tumors.

Nanomedicine. 2019-5-17

[9]
Tailoring the photoluminescence of atomically precise nanoclusters.

Chem Soc Rev. 2019-4-15

[10]
Sizing protein-templated gold nanoclusters by time resolved fluorescence anisotropy decay measurements.

Spectrochim Acta A Mol Biomol Spectrosc. 2017-12-9

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