Antoine Rodolphe, Maysinger Dusica, Sancey Lucie, Bonačić-Koutecký Vlasta
Institut Lumière Matière UMR 5306, Université Claude Bernard Lyon 1, CNRS, Univ Lyon, F- 69100, Villeurbanne, France.
Department of Pharmacology & Therapeutics, McGill University, Montréal, QC, H3G 1Y6, Canada.
Commun Chem. 2022 Apr 6;5(1):47. doi: 10.1038/s42004-022-00665-9.
Interfacing ultrasmall metal nanoclusters (NCs) with proteins can present a dual opportunity: proteins can be used for protecting NCs, and the surface ligands of NCs may interact with proteins. Here, the authors identify and discuss remaining open questions surrounding the bio-NC interface that call for future research efforts.
将超小型金属纳米团簇(NCs)与蛋白质结合可带来双重机遇:蛋白质可用于保护纳米团簇,且纳米团簇的表面配体可能与蛋白质相互作用。在此,作者识别并讨论了围绕生物纳米团簇界面仍未解决的开放性问题,这些问题需要未来的研究努力。