Department of Radiology, Brain Hospital of Hunan Province (Hunan Second People's Hospital), Changsha 410007, China.
Curr Med Imaging. 2023;19(14):1685-1688. doi: 10.2174/1573405619666230125112459.
Pediatric pituitary adenomas are rare, resulting in a limited amount of literature on these patients. The incidence of calcification in adult patients with pituitary adenomas is only 0.2% to 8%, while the incidence of calcification in children has not been reported.
In this paper, we report a 10-year-old girl with a calcified pituitary adenoma. Laboratory examination showed the growth hormone (GH) to be more than 50ug/L, and pituitary prolactin (PRL) was 27.42 ng/mL. Non-contrast-enhanced computed tomography (CT) scans indicated a large sellar occupation with multiple nodules of calcification. Subsequently, the patient underwent a transcranial resection. Histopathologic evaluation confirmed the diagnosis of pituitary adenoma with multiple calcifications.
Since the management and prognosis of adenomas with calcification from other occupations of the pituitary gland differ significantly, it is important to differentiate between the two.
儿童垂体腺瘤较为罕见,因此针对此类患者的文献报道数量有限。成人垂体腺瘤的钙化发生率仅为 0.2%至 8%,而儿童的钙化发生率尚未见报道。
本文报道了一例 10 岁女孩患有钙化性垂体腺瘤。实验室检查显示生长激素(GH)超过 50ug/L,垂体催乳素(PRL)为 27.42ng/mL。非增强 CT 扫描显示鞍内大占位,伴有多处钙化结节。随后,患者接受了经颅切除术。组织病理学评估证实了垂体腺瘤伴多发钙化的诊断。
由于伴有钙化的腺瘤与其他垂体占位性病变的处理和预后有显著差异,因此鉴别这两者非常重要。