文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

传统草药胡（覆盆子）的生物活性成分、药理作用及药物开发

Bioactive components, pharmacological effects, and drug development of traditional herbal medicine Hu (Fu-Pen-Zi).

作者信息

He Beihui, Dai Linghao, Jin Li, Liu Yuan, Li Xiaojuan, Luo Minmin, Wang Zhian, Kai Guoyin

机构信息

The First Affiliated Hospital, Zhejiang Provincial Hospital of Chinese Medicine, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Zhejiang Research Institute of Traditional Chinese Medicine Co., Ltd., Hangzhou, China.

出版信息

Front Nutr. 2023 Jan 9;9:1052504. doi: 10.3389/fnut.2022.1052504. eCollection 2022.

DOI:10.3389/fnut.2022.1052504
PMID:36698464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9868258/
Abstract

Hu (Chinese Raspberry), known as Fu-Pen-Zi in Chinese, a woody perennial plant of the genus Rubus in the Rosaceae family, has specific nutritional and medicinal values, which is considered food-medicine herb in China for thousands of years to treat impotence, premature ejaculation, enuresis, frequent urination, and other diseases. This review aims to summarize recent advances in the bioactive components, pharmacological effects, and drug development and utilization of Hu, hoping to provide useful support for its further research and clinical application. The bioactive components in Hu contain mainly terpenoids, flavonoids, alkaloids, phenolic acids, polysaccharides, and steroids. The main pharmacological effects are their anti-oxidant, anti-inflammatory, and anti-tumor capacity on human health. Hu is a very valuable food-medicine herb. The development of Hu-related drugs is relatively single, which is limited to traditional Chinese medicine and prescriptions. Therefore, it is vital to pay interest to Hu and its bioactive components in the future and extend its scientific application.

摘要

覆盆子，中药名为覆盆 子，是蔷薇科悬钩子属多年生木本植物，具有独特的营养和药用价值，数千年来在中国被视为药食同源的草药，用于治疗阳痿、早泄、遗尿、尿频等疾病。本综述旨在总结覆盆子生物活性成分、药理作用以及药物开发利用方面的最新研究进展，以期为其进一步研究和临床应用提供有益参考。覆盆子中的生物活性成分主要包括萜类、黄酮类、生物碱、酚酸、多糖和甾体类化合物。其主要药理作用体现在对人体健康具有抗氧化、抗炎和抗肿瘤能力。覆盆子是一种极具价值的药食同源草药。目前与覆盆子相关的药物开发相对单一，局限于传统中药及方剂。因此，未来关注覆盆子及其生物活性成分并拓展其科学应用至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/c2249bbb9611/fnut-09-1052504-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/ce5ab038288a/fnut-09-1052504-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/3fe3588258e6/fnut-09-1052504-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/e4ea6485e704/fnut-09-1052504-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/92b7c931fbb6/fnut-09-1052504-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/c2249bbb9611/fnut-09-1052504-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/ce5ab038288a/fnut-09-1052504-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/3fe3588258e6/fnut-09-1052504-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/e4ea6485e704/fnut-09-1052504-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/92b7c931fbb6/fnut-09-1052504-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/9868258/c2249bbb9611/fnut-09-1052504-g0005.jpg

相似文献

[1]
Bioactive components, pharmacological effects, and drug development of traditional herbal medicine Hu (Fu-Pen-Zi).

Front Nutr. 2023-1-9

[2]
Hu: A Review of the Phytochemistry and Pharmacology.

Front Pharmacol. 2019-7-16

[3]
The chromosome-scale reference genome of Rubus chingii Hu provides insight into the biosynthetic pathway of hydrolyzable tannins.

Plant J. 2021-9

[4]
Rubus chingii Hu: an overview of botany, traditional uses, phytochemistry, and pharmacology.

Chin J Nat Med. 2020-6

[5]
Combined transcriptomic and metabolic analyses reveal potential mechanism for fruit development and quality control of Chinese raspberry (Rubus chingii Hu).

Plant Cell Rep. 2021-10

[6]
Chemical composition, pharmacological activity and development strategies of : A review.

Chin Herb Med. 2024-5-22

[7]
Bioactive comparison of main components from unripe fruits of Rubus chingii Hu and identification of the effective component.

Food Funct. 2015-7

[8]
Extraction of antioxidant and antiproliferative ingredients from fruits of Hu by active tracking guidance.

Medchemcomm. 2017-6-28

[9]
The antioxidant compounds isolated from the fruits of chinese wild raspberry Hu.

Nat Prod Res. 2018-10-22

[10]
Integrated analysis of multiple metabolome and transcriptome revealed the accumulation of flavonoids and associated molecular regulation mechanisms in Rubus chingii Hu at different developmental stages.

Plant Physiol Biochem. 2023-11

引用本文的文献

[1]
Biological Effects of Species in Skin Disorders-An Up-To-Date Overview.

Plants (Basel). 2025-5-24

[2]
Preparation, structural characterization and health benefits of polysaccharides from Hu: a review.

Front Pharmacol. 2025-5-9

[3]
The role and mechanism of "eight famous herbals in Zhejiang" in cancer via network pharmacology and experimental validation.

Front Oncol. 2024-11-15

[4]
Characteristics and phylogenetic analysis of the complete chloroplast genome of Hu 1925 from the family Rosaceae.

Mitochondrial DNA B Resour. 2023-11-20

[5]
Genetic Diversity Analysis and Core Germplasm Construction of Hu.

Plants (Basel). 2024-2-23

[6]
Effects of different drying methods on Hu fruit during processing.

Heliyon. 2024-1-14

[7]
Integrated 16s RNA sequencing and network pharmacology to explore the effects of polyphenol-rich raspberry leaf extract on weight control.

Front Nutr. 2024-1-8

[8]
Multi-component analyses of raspberry: Optimization of extraction procedure and network pharmacology.

Heliyon. 2023-11-4

[9]
as a Source of Bioactive Chemical Compounds with an Important Role in Human Health and Comparison of the Antioxidant Potential of Fruits and Juice of Three Repeat-Fruiting L. Cultivars.

Metabolites. 2023-11-2

[10]
TCM "medicine and food homology" in the management of post-COVID disorders.

Front Immunol. 2023

本文引用的文献

[1]
Oleanolic Acid: Extraction, Characterization and Biological Activity.

Nutrients. 2022-1-31

[2]
Potential metabolic activities of raspberry ketone.

J Food Biochem. 2022-1

[3]
ER-Mitochondria Calcium Flux by β-Sitosterol Promotes Cell Death in Ovarian Cancer.

Antioxidants (Basel). 2021-10-8

[4]
Complexation of ellagic acid with α-lactalbumin and its antioxidant property.

Food Chem. 2022-3-15

[5]
Combined transcriptomic and metabolic analyses reveal potential mechanism for fruit development and quality control of Chinese raspberry (Rubus chingii Hu).

Plant Cell Rep. 2021-10

[6]
Emerging impact of quercetin in the treatment of prostate cancer.

Biomed Pharmacother. 2021-6

[7]
Molecular mechanisms underlying macrophage immunomodulatory activity of Rubus chingii Hu polysaccharides.

Int J Biol Macromol. 2021-8-31

[8]
The chromosome-scale reference genome of Rubus chingii Hu provides insight into the biosynthetic pathway of hydrolyzable tannins.

Plant J. 2021-9

[9]
Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS.

J Pharm Biomed Anal. 2021-9-5

[10]
Rat plasma protein binding of kaempferol-3-O-rutinoside from Lu'an GuaPian tea and its anti-inflammatory mechanism for cardiovascular protection.

J Food Biochem. 2021-7

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索