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面对未知:特发性巨细胞性肝炎

Facing the Unknown: Idiopathic Giant Cell Hepatitis.

作者信息

McGoldrick Meaghan, Castrodad-Rodríguez Carlos A, Huang Yan, Tow Clara

机构信息

Department of Medicine, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY.

Department of Pathology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY.

出版信息

ACG Case Rep J. 2023 Jan 20;10(1):e00966. doi: 10.14309/crj.0000000000000966. eCollection 2023 Jan.

DOI:10.14309/crj.0000000000000966
PMID:36699191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9857266/
Abstract

Giant cell hepatitis is a rare infiltrative disease associated with several viruses, drugs, malignancies, and autoimmune conditions. To date, treatment aims at controlling the underlying etiology, and there are limited data on the clinical course and treatment of idiopathic cases. We present a case of idiopathic giant cell hepatitis in an otherwise healthy adult man and review the literature regarding treatment and outcomes in this population.

摘要

巨细胞性肝炎是一种罕见的浸润性疾病,与多种病毒、药物、恶性肿瘤及自身免疫性疾病相关。迄今为止,治疗旨在控制潜在病因,而关于特发性病例的临床病程和治疗的数据有限。我们报告一例原本健康的成年男性特发性巨细胞性肝炎病例,并综述该人群的治疗及预后相关文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d234/9857266/7a6357b911e3/ac9-10-e00966-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d234/9857266/7a6357b911e3/ac9-10-e00966-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d234/9857266/7a6357b911e3/ac9-10-e00966-g001.jpg

相似文献

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Facing the Unknown: Idiopathic Giant Cell Hepatitis.面对未知:特发性巨细胞性肝炎
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本文引用的文献

1
Autoimmune post-infantile giant cell hepatitis: a case report and review of the literature.自身免疫性婴儿期后巨细胞性肝炎:一例报告及文献复习
Can Liver J. 2021 Apr 29;4(2):104-109. doi: 10.3138/canlivj-2020-0024. eCollection 2021 Spring.
2
[A case of idiopathic postinfantile giant cell hepatitis treated with a calcineurin inhibitor].1例用钙调神经磷酸酶抑制剂治疗的特发性婴儿期后巨细胞性肝炎
Dtsch Med Wochenschr. 2021 Feb;146(3):193-197. doi: 10.1055/a-1323-5057. Epub 2021 Jan 29.
3
Post-infantile giant cell hepatitis: A single center's experience over 25 years.
婴儿期后巨细胞性肝炎:一家中心25年的经验
World J Hepatol. 2019 Dec 27;11(12):752-760. doi: 10.4254/wjh.v11.i12.752.
4
Management of giant cell hepatitis associated with chronic lymphocytic leukemia - a case series and review of the literature.巨细胞肝炎合并慢性淋巴细胞白血病的治疗:病例系列及文献复习。
Cancer Biol Ther. 2019;20(8):1136-1140. doi: 10.1080/15384047.2019.1598763. Epub 2019 May 15.
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Postinfantile giant cell hepatitis: an etiological and prognostic perspective.婴儿期后巨细胞性肝炎:病因及预后分析
Hepat Res Treat. 2013;2013:601290. doi: 10.1155/2013/601290. Epub 2013 Mar 11.
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Recurrent, progressive giant cell hepatitis in two consecutive liver allografts in a middle-aged woman.一名中年女性连续两次肝移植后出现复发性、进行性巨细胞性肝炎。
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Syncytial giant-cell hepatitis. Sporadic hepatitis with distinctive pathological features, a severe clinical course, and paramyxoviral features.合体细胞巨细胞性肝炎。一种具有独特病理特征、严重临床病程及副粘病毒特征的散发性肝炎。
N Engl J Med. 1991 Feb 14;324(7):455-60. doi: 10.1056/NEJM199102143240705.