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[标准化身体机能测试与衰弱表型作为八十岁老人不良事件预测指标的比较]

[A standardised physical performance test versus the frailty phenotype as predictors of adverse events in octogenarians].

作者信息

Benats Floriane, Vaes Bert, Hegendörfer Eralda, Degryse Jean-Marie

机构信息

Institut de recherche santé et société, Université catholique de Louvain, Bruxelles, Belgique

Department of Public Health and Primary Care Katholieke Universiteit Leuven, Louvain, Belgique

出版信息

Geriatr Psychol Neuropsychiatr Vieil. 2022 Dec 1;20(4):439-456. doi: 10.1684/pnv.2022.1065.

Abstract

BACKGROUND

The population of adults aged 80 years and older is heterogenous with some being robust and others having a higher risk for adverse events. This study compares the predictive value of two tools used to identify older adults who are at higher risk for adverse outcomes: frailty phenotype according to Fried and a standardized physical performance test.

METHODS

The BELFRAIL population-based cohort of 567 community-dwelling adults aged 80 years and older living in Belgium. Fried frailty phenotype and physical performance test (gait, chair stand, standing balance tests and putting on and off a cardigan). The predictive value of the two tools in predicting mortality (up to 5.1 ± 0.25 years), hospitalization (3.0 ± 0.25 years) and decline in activities of daily living (after 1.7 ± 0.21 years) was compared using reclassification statistics and decision curve analysis.

RESULTS

Frail participants according to Fried phenotype and those in the lowest quartile of the physical performance test score had higher risk for mortality and hospitalization. Harrell C and area under operator curve were similar (< 0.70). Reclassification statistics and net benefit in decision curve analysis showed no significant difference between the two tools in identifying higher risk for mortality, hospitalization and functional decline.

CONCLUSION

In a cohort of community-dwelling adults 80 years and older a standardized physical performance test was as good as the Fried frailty phenotype in identifying higher risk for adverse outcomes.

摘要

背景

80岁及以上的成年人群具有异质性,一些人身体强健,而另一些人发生不良事件的风险较高。本研究比较了两种用于识别不良结局风险较高的老年人的工具的预测价值:根据弗里德标准的衰弱表型和标准化身体功能测试。

方法

基于比利时567名年龄在80岁及以上的社区居住成年人的BELFRAIL队列。评估弗里德衰弱表型和身体功能测试(步态、从椅子上站起、站立平衡测试以及穿脱开襟羊毛衫)。使用重新分类统计和决策曲线分析比较这两种工具在预测死亡率(长达5.1±0.25年)、住院率(3.0±0.25年)和日常生活活动能力下降(1.7±0.21年后)方面的预测价值。

结果

根据弗里德表型判定为衰弱的参与者以及身体功能测试分数处于最低四分位数的参与者死亡和住院风险更高。哈雷尔C统计量和操作特征曲线下面积相似(<0.70)。重新分类统计和决策曲线分析中的净效益表明,在识别死亡、住院和功能下降的较高风险方面,这两种工具之间没有显著差异。

结论

在一个80岁及以上的社区居住成年人群体中,标准化身体功能测试在识别不良结局较高风险方面与弗里德衰弱表型效果相当。

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